Nicotine emissions from electronic cigarettes: Individual and interactive effects of propylene glycol to vegetable glycerin composition and device power output
Nicotine emissions from electronic cigarettes: Individual and interactive effects of propylene glycol to vegetable glycerin composition and device power output
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DOI：
10.1016/j.fct.2018.03.025
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发表时间：
2018-05-01
影响因子：
4.3
通讯作者：
Goniewicz, Maciej Lukasz
中科院分区：
文献类型：
--
作者：
Kosmider, Leon;Spindle, Tory R.;Goniewicz, Maciej Lukasz
简介：电子烟的功率输出差异很大，这些产品所用液体的成分也有很大差异。大多数电子烟液体含有两种主要溶剂：丙二醇（PG）和植物甘油（VG）。本研究的主要目的是检查 PG 和 VG 成分以及设备功率相互作用对电子烟尼古丁排放量的影响程度。方法：使用第二代电子烟和自动吸烟机产生气溶胶。通过气相色谱法测量气溶胶中的尼古丁，这些溶液由含有纯 PG、纯 VG 或两种溶剂的混合物 (50:50) 的三种溶液在三种不同的功率设置（4.3、6.7 和 9.6 W）下产生。结果：在最低功率设置下，随着溶液中添加更多的 PG，尼古丁产量显着增加。然而，随着设备功率的增加，不同液体的尼古丁产量差异变得不那么明显。在最高功率设置（9.6 W）下，所检查的三种液体的尼古丁产量没有差异。结论：本研究表明，电子烟液体 PG 和 VG 成分影响尼古丁排放的程度取决于设备功率。因此，相对于溶剂浓度，设备功率可能更大程度地影响电子烟尼古丁排放。
Introduction: The power output of e-cigarettes varies considerably, as does the composition of liquids used with these products. Most e-cigarette liquids contain two primary solvents: propylene glycol (PG) and vegetable glycerin (VG). The primary aim of this study was to examine the extent to which PG and VG composition and device power interact with each other to influence e-cigarette nicotine emissions.Methods: Aerosols were generated using a 2nd generation e-cigarette and an automatic smoking machine. Nicotine was measured in aerosols, via gas chromatography, produced from three solutions containing pure PG, pure VG, or a mixture of both solvents (50:50) across three different power settings (4.3, 6.7, and 9.6 W).Results: At the lowest power setting, nicotine yield increased significantly as more PG was added to the solution. However, as device power was increased, differences in nicotine yield across liquids became less pronounced. At the highest power setting (9.6 W), nicotine yields did not differ across the three liquids examined.Conclusions: The present study demonstrated that the extent to which e-cigarette liquid PG and VG composition influences nicotine emissions is dependent on device power. Thus, device power may influence e-cigarette nicotine emissions to a greater degree relative to solvent concentrations.