Stiffness estimation of transversely anisotropic materials using a novel indentation tester with a rectangular hole
Stiffness estimation of transversely anisotropic materials using a novel indentation tester with a rectangular hole
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使用新型矩形孔压痕测试仪估计横向各向异性材料的刚度
DOI：
10.1080/10255842.2022.2098015
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发表时间：
2022
影响因子：
1.6
通讯作者：
Matsumoto Takeo
中科院分区：
文献类型：
--
作者：
Tamura Atsutaka;Saiki Mika;Hongu Jun-ichi;Matsumoto Takeo
由于胚胎在原肠胚形成阶段会急剧改变其形态，因此年轻胚胎的机械特性很重要，因为它们也会随着发育阶段改变其组织硬度。在这里，虚拟压缩试验进行了假设的非洲爪蟾laevisgastrula具有横向各向异性的球形形状。基于实验设计，我们发现，杨氏模量和材料各向异性可以有效地确定通过测量的反作用力和表面位移时，压痕测试机到一个胚胎。提出的方案可能是一个实质性的一步，了解胚胎发育过程中细胞类型的规范的时间。
Since embryos change their morphology drastically in the gastrulation stage, mechanical characterization of young embryos is important as they also change their tissue stiffness with the stage of development. Herein, virtual compression tests were conducted assuming that theXenopus laevisgastrula has a spherical shape with transverse anisotropy. Based on the design of experiments, we found that the Young’s moduli and material anisotropy can be efficiently determined by measuring the reaction force and surface displacement when indenting the tester into an embryo. The proposed scheme may be a substantial step toward understanding the timing of cell-type specification during embryo development.
影响因子：
6.8
作者：
AKAIKE, H
通讯作者：
AKAIKE, H