Splanchnic somatostatin: a hormonal regulator of nutrient homeostasis.
Splanchnic somatostatin: a hormonal regulator of nutrient homeostasis.
复制标题
内脏生长抑素：营养稳态的激素调节剂。
作者：
V. Schusdziarra;E. Zyznar;D. Rouiller;Guenther Boden;J. Brown;Akira Arimura;R. Unger
在接受测试餐的狗的动脉血浆中发现了游离的（约 1600 道尔顿）生长抑素样免疫反应性。当狗吃脂肪餐时，循环中的生长抑素的中和增加了餐后甘油三酯、胃泌素、胰多肽和胰岛素的血浆浓度。结论是，对于狗来说，生长抑素是一种真正的激素，可以调节营养物质从肠道到内部环境的移动。
Free (approximately 1600 daltons) somatostatin-like immunoreactivity was identified in arterial plasma of dogs that had received a test meal. Neutralization of circulating somatostatin while the dogs were consuming a fatty meal increased the plasma concentrations of triglycerides, gastrin, pancreatic polypeptide, and insulin after the meal. It is concluded that, in the dog, somatostatin is a true hormone that regulates the movement of nutrients from the gut to the internal environment.