Biodegradable and biocompatible high elastic chitosan scaffold is cell-friendly both in vitro and in vivo

Biodegradable and biocompatible high elastic chitosan scaffold is cell-friendly both in vitro and in vivo
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可生物降解且生物相容的高弹性壳聚糖支架在体外和体内均对细胞友好

DOI:
10.18632/oncotarget.14709
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发表时间:
2017-05-30
期刊:
影响因子:
--
通讯作者:
Hu, Qiaoling
Hu, Qiaoling
中科院分区:
其他
文献类型:
--
作者:
Pang, Yichuan;Qin, An;Hu, Qiaoling

文献摘要

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Biodegradable and biocompatible macromolecule chitosan has been favored for a variety of clinical applications. We reported herein the fabrication of a novel chitosan scaffold with high elasticity. This scaffold can be easily compressed and thus enable the insertion of such scaffold into surgical lesions during minimal invasive surgeries. In addition, this novel scaffold can restore its shape when released. We evidenced that this high elastic scaffold has better biocompatibility than traditional chitosan scaffold. Therefore, this new chitosan material might lead to the manufacture of a variety of novel biodegradable biomedical materials and devices.