Physostigmine: an antidote for excessive central nervous system depression or paradoxical rage reactions resulting from intravenous diazepam.
Physostigmine: an antidote for excessive central nervous system depression or paradoxical rage reactions resulting from intravenous diazepam.
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毒扁豆碱：一种解毒剂，用于治疗中枢神经系统过度抑制或静脉注射地西泮引起的矛盾愤怒反应。
作者：
Jastak Jt
综述了药理学和药物的使用。特别令人感兴趣的是该药物能够逆转静脉注射安定（Valium®）和其他临床可用的苯二氮卓类药物引起的过度嗜睡或矛盾反应。本文讨论了其用于抗胆碱能综合征的治疗，并记录了其副作用的发生率和特征。提出了适当的紧急使用建议。
A review of the pharmacology and use of the drug physostigmine is presented. Of particular interest is the drug's capability to reverse excessive somnolence or paradoxical responses caused by intravenous diazepam (Valium®) and other clinically available benzodiazepines. Its use for the treatment of anticholinergic syndrome is discussed and incidence and characterization of side effects documented. Recommendations are made for appropriate emergency use.