Determination of aromatic amines formed from azo colorants in toy products
Determination of aromatic amines formed from azo colorants in toy products
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DOI：
10.1016/s0021-9673(02)01162-7
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发表时间：
2002-11-08
影响因子：
4.1
通讯作者：
Jiménez, A
中科院分区：
文献类型：
--
作者：
Garrigós, MC;Reche, F;Jiménez, A
对玩具中常用的偶氮染料还原后生成的芳香胺进行了测定研究。二亚硫酸钠用于偶氮基的还原裂解，释放的胺随后用高效液相色谱-紫外检测进行分析。用全水平析因设计研究了与还原过程相关的不同变量的影响，其中最显著的参数以及顺序交互作用被研究了。通过研究不同亚硫酸盐/着色剂比例下得到的胺量的变化，得到了每种着色剂的还原曲线。检测到形成偶氮染料的预期芳香胺，并且在硝基的存在下观察到进一步的还原。通过向着色剂中添加不同量的胺来确定总还原过程的产率。(C)2002 Elsevier Science B.V.保留所有权利。
A study for the determination of the aromatic amines formed after reduction of the azo colorants mostly used in toys was conducted. Sodium dithionite was used in the reductive cleavage of the azo group for the dyes, and the released amines were subsequently analysed by high-performance liquid chromatography with UV detection. The influence of different variables related to the reduction process was investigated by the use of a full-level factorial design, where most significant parameters as well as order interactions were studied. Reduction profiles for each colorant were obtained by studying the changes in the amount of amine obtained with different dithionite/colorant ratios. The expected aromatic amines forming azo colorants were detected, and in the presence of a nitro group a further reduction was observed. The yield of the total reduction process was determined by using standard addition of different quantities of amines to the colorants. (C) 2002 Elsevier Science B.V. All rights reserved.