Lifetime risk of being diagnosed with, or dying from, prostate cancer by major ethnic group in England 2008-2010.

Lifetime risk of being diagnosed with, or dying from, prostate cancer by major ethnic group in England 2008-2010.
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DOI:
10.1186/s12916-015-0405-5
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发表时间:
2015-07-30
期刊:
影响因子:
9.3
通讯作者:
Cooper A
Cooper A
中科院分区:
医学1区
文献类型:
--
作者:
Lloyd T;Hounsome L;Mehay A;Mee S;Verne J;Cooper A

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在英国,男性终生被诊断出患有前列腺癌的风险为八分之一。我们按主要种族计算了被诊断出患有前列腺癌和死于前列腺癌的终生风险。英国公共卫生部门提供了英国(2008-2010 年)按主要种族划分的前列腺癌发病率和死亡率数据。种族和死亡率数据不完整,在使用 DevCan(百分比、范围)计算终生风险之前需要进行各种假设和调整。白人男性终生被诊断患有前列腺癌的风险约为八分之一(13.3%,13.2-15.0%),黑人男性为四分之一(29.3%,23.5-37.2%),亚洲男性为十三分之一(7.9%,6.3-10.5%),而死于前列腺癌的风险约为二十四分之一(4.2%, 4.2–4.7%) 为白人男性,每 12 人中就有 1 人 (8.7%, 7.6–10.6%) 为黑人男性,每 44 人中就有 1 人 (2.3%, 1.9–3.0%) 为亚裔男性。在英格兰,黑人被诊断出患有前列腺癌和死于前列腺癌的风险是白人的两倍。这是向黑人传达的重要信息。被诊断出患有前列腺癌的白人、黑人和亚洲男性死于这种疾病的可能性相同,与种族无关。尽管如此,在英国,死于前列腺癌的黑人男性比例仍然较高。本文的在线版本 (doi:10.1186/s12916-015-0405-5) 包含补充材料,可供授权用户使用。
In the UK, a man’s lifetime risk of being diagnosed with prostate cancer is 1 in 8. We calculated both the lifetime risk of being diagnosed with and dying from prostate cancer by major ethnic group. Public Health England provided prostate cancer incidence and mortality data for England (2008–2010) by major ethnic group. Ethnicity and mortality data were incomplete, requiring various assumptions and adjustments before lifetime risk was calculated using DevCan (percent, range). The lifetime risk of being diagnosed with prostate cancer is approximately 1 in 8 (13.3 %, 13.2–15.0 %) for White men, 1 in 4 (29.3 %, 23.5–37.2 %) for Black men, and 1 in 13 (7.9 %, 6.3–10.5 %) for Asian men, whereas that of dying from prostate cancer is approximately 1 in 24 (4.2 %, 4.2–4.7 %) for White men, 1 in 12 (8.7 %, 7.6–10.6 %) for Black men, and 1 in 44 (2.3 %, 1.9–3.0 %) for Asian men. In England, Black men are at twice the risk of being diagnosed with, and dying from, prostate cancer compared to White men. This is an important message to communicate to Black men. White, Black, and Asian men with a prostate cancer diagnosis are all as likely to die from the disease, independent of their ethnicity. Nonetheless, proportionally more Black men are dying from prostate cancer in England. The online version of this article (doi:10.1186/s12916-015-0405-5) contains supplementary material, which is available to authorized users.