Gene regulation in Aspergillus:: From genetics to genomics
Gene regulation in Aspergillus:: From genetics to genomics
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DOI：
10.1080/13693780600835781
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发表时间：
2006-09-01
期刊：
影响因子：
2.9
通讯作者：
Jones, Meriel G.
中科院分区：
文献类型：
--
作者：
Caddick, Mark X.;Dobson, Chris;Jones, Meriel G.
任何生物体成功的一个基本方面是能够有效地监测和应对其环境，这一过程主要是通过适当调节基因表达来实现的。很少有比真菌更好的例子了，它们栖息在从落叶到人体的各种各样的、往往是恶劣的环境中。调节可以发生在许多层面上，当我们详细研究特定的基因时，这种模式越来越复杂。我们将简要回顾已知在曲霉属中发生调节的不同层面，以及从现有基因组序列中获得的见解。
A fundamental aspect of any organism's success is the ability to monitor and respond effectively to its environment, a process which is largely achieved through the appropriate regulation of gene expression. There are few better examples than fungi, which inhabit diverse and often hostile environments, ranging from leaf litter to the human body. Regulation can occur at many levels, and as we investigate specific genes in detail, the paradigm is one of increasing complexity We will briefly review the different levels at which regulation is known to occur in Aspergillus and the insights gained from the available genome sequences.