Computer analysis of physiologic signals in a cardiovascular research laboratory.

Computer analysis of physiologic signals in a cardiovascular research laboratory.
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心血管研究实验室中生理信号的计算机分析。

DOI:
10.1016/0010-4825(91)90018-5
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发表时间:
1991
影响因子:
7.7
通讯作者:
Nicklas,JM
Nicklas,JM
中科院分区:
工程技术2区
文献类型:
--
作者:
Greenhut,SE;Lee,JW;Monsur,JC;Nicklas,JM

文献摘要

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一个综合的计算机程序,提供即时计算和反馈已开发的数据采集和分析信号在心血管动物实验室。该系统以微电脑为基础,配备模数转换器,支持多达8个同时采样的心血管信号的数字化、滤波和微分功能模块。该程序检测,分析,并绘制传入和平均节拍。对每个通道进行逐拍信号平均,并自动划分心脏周期。对于每个心脏周期和平均周期,测量了6个生理基准标记的振幅并进行了推导计算。通道vs通道图和环路面积测量也计算和显示。在犬类心血管数据测试中,计算机算法已被证明可以给出准确、精确和可重复的结果。此外,还证明了信号平均是一种合适的心血管信号分析技术。
A comprehensive computer program which provides immediate computation and feedback has been developed for data acquisition and analysis of signals in a cardiovascular animal laboratory. The system is based on a microcomputer equipped with analog-to-digital converter and supports function modules which digitize, filter, and differentiate up to 8 simultaneously sampled cardiovascular signals. The program detects, analyses, and plots incoming and averaged beats. Beat-by-beat signal averaging for each channel is performed and cardiac cycles are partitioned automatically. For each cardiac and average cycle the amplitude at 6 physiologic fiducial markers are measured and derived calculations are made. Channel vs channel plots and loop area measurements are also computed and displayed. The computer algorithms have been shown to give accurate, precise, and reproducible results when tested on canine cardiovascular data. Also, it has been demonstrated that signal averaging is an appropriate analysis technique for cardiovascular signals.