Electroluminescence as a probe for electrical and optical properties of deoxyribonucleic acid
Electroluminescence as a probe for electrical and optical properties of deoxyribonucleic acid
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电致发光作为脱氧核糖核酸电学和光学性质的探针
DOI：
10.1117/12.457483
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发表时间：
2002
期刊：
影响因子：
--
通讯作者：
N. Ogata
中科院分区：
文献类型：
--
作者：
Tamami Koyama;Y. Kawabe;N. Ogata
掺杂在源自鲑鱼的脱氧核糖核酸 (DNA) 中的几类染料由于抑制分子聚集而显示出荧光增强。此外，最近的一些研究支持 DNA 链的导电性。这些特性的结合表明开发基于生物聚合物系统的有机 LED 器件 (OLED) 的可能性。此外，电致发光（EL）效应可以用作DNA电学和光学特性的探针。我们制造了基于 DNA-脂质复合物和掺杂染料（溴化乙锭和荧光素）的 OLED 器件。器件由空穴注入层、染料掺杂的DNA-脂质层和电极组成。具有溴化乙锭掺杂 DNA 的 OLED 在 DC 偏压下显示 LED 发射，但发射源是用作电子转运体的三-(8-羟基喹啉)铝(III)(Alq3)。器件的电流-电压特性显示出明显的整流行为。从这些实验结果可以证实DNA在外部直流偏压下传输空穴电流。当使用荧光素作为 DNA 中的掺杂剂并制造没有 Alq3 层的器件时，我们观察到掺入 DNA 的染料发出的发射光。虽然光谱中发射中心的来源尚不清楚，但表明如果进一步改进，DNA-脂质复合物将基本适用于OLED。
Several class of dyes doped in deoxyribonucleic acid (DNA) derived from salmon show enhancement of fluorescence due to suppression of molecular aggregation. Also, some recent studies support electric conduction in DNA strands. Combination of these properties suggests the possibility to develop organic LED devices (OLED) based on biopolymer systems. Furthermore, the electroluminescence (EL) effect can be employed as a probe for electrical and optical properties of DNA. We fabricated OLED devices based on DNA- lipid complex and dopant dyes (ethidium bromide and fluorescein). Devices are composed of hole injection layer, dye-doped DNA-lipid layer and electrodues. OLED with ethidium bromide doped DNA showed LED emission under DC bias, but the origin of the emission was tris-(8- hydroxyquinolinato)aluminum(III)(Alq3) which was employed as an electron transporter. The current-voltage characteristics of the devices show apparent rectification behavior. From these experimental results, it is confirmed that DNA transports hole current under external DC bias. When employing fluorescein as a dopant in DNA and fabricating the devices without Alq3 layer, we observed emission from the dyes incorporated in DNA. Although the origins of the emission centers in spectra are not clear, it shows that the DNA-lipid complex will be basically applicable to OLED if additional improvements are made.