PROJECTION FROM THE SENSORY TO THE MOTOR CORTEX IS IMPORTANT IN LEARNING MOTOR-SKILLS IN THE MONKEY
PROJECTION FROM THE SENSORY TO THE MOTOR CORTEX IS IMPORTANT IN LEARNING MOTOR-SKILLS IN THE MONKEY
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DOI：
10.1152/jn.1993.70.2.733
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发表时间：
1993-08-01
影响因子：
2.5
通讯作者：
ASANUMA, H
中科院分区：
文献类型：
--
作者：
PAVLIDES, C;MIYASHITA, E;ASANUMA, H
1.从躯体感觉皮层到初级运动皮层的投射被认为在学习新的运动技能中起着重要作用。通过研究感觉皮层损伤对新运动技能学习的影响来验证这一假设.我们使用了两个实验范式来揭示损伤对新运动技能学习的影响。其中一项任务是捕捉以不同速度下落的食物颗粒。另一项任务是从旋转的杠杆上抓住一个食物颗粒。这两项任务都需要获得新的运动技能。训练是在一侧半球的体感皮层手部区域受损后开始的。在这两项任务中，猴子在学习新技能时，与完整半球对侧的手相比，用消融的躯体感觉皮层对侧的手有严重的困难。在获得对侧手的运动技能后。完整半球，躯体感觉皮层手区的损伤不影响学习的运动技能.在对照实验中，猴子被训练从旋转板上捡起食物颗粒。这项任务不需要获得新的运动技能，但可以通过利用现有的运动技能来执行。训练前后躯体感觉皮层的损伤并不影响任何一只手完成这项任务。它的结论是，皮质投射从躯体感觉到运动皮层起着重要的作用，在学习新的运动技能，但不是在执行现有的运动技能。
1. The projection from the somatosensory cortex to the primary motor cortex has been proposed to play an important role in learning novel motor skills. This hypothesis was examined by studying the effects of lesions to the sensory cortex on learning of new motor skills.2. We used two experimental paradigms to reveal the effects of lesions on learning of new motor skills. One task was to catch a food pellet falling at various velocities. The other task was to catch a food pellet from a rotating lever. Both tasks required acquisition of novel motor skills.3. The training was started after a lesion of the hand area in the somatosensory cortex of one hemisphere. In both tasks, monkeys had severe difficulty in learning the new skills with the hand contralateral to the ablated somatosensory cortex, compared with the hand contralateral to the intact hemisphere.4. After acquisition of the motor skill in the hand contralateral to. intact hemisphere, lesion of the somatosensory cortex hand area did not abolish the learned motor skill.5. In control experiments, monkeys were trained to pick up a food pellet from a rotating board. This task did not necessitate acquisition of new motor skills, but could be performed by utilizing existing motor skills. Lesion in the somatosensory cortex before or after the training did not affect the execution of this task by either hand.6. It is concluded that the corticocortical projection from the somatosensory to the motor cortex plays an important role in learning new motor skills, but not in the execution of existing motor skills.