Influence of somatostatin on gastric motility and meal absorption in rhesus monkeys, Macaca mulatta.
Influence of somatostatin on gastric motility and meal absorption in rhesus monkeys, Macaca mulatta.
复制标题
生长抑素对恒河猴胃动力和膳食吸收的影响。
DOI：
10.1016/0026-0495(81)90112-8
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
Hansen,BC
中科院分区：
文献类型：
--
作者：
Koerker,DJ;Hansen,BC
在清醒恒河猴（M。mulatta）。用~ 3 H-3-葡萄糖和~ 3 H-9，10-三油酸甘油酯标记的全流质饲料灌胃前和灌胃后2小时，分别连续输注生理盐水或生长抑素（0.8 μg/kg × min）。通过记录胃压和腔外应变仪评估胃动力。静脉注射生长抑素并没有改变胃运动或标记葡萄糖的吸收率，但脂质吸收明显受损。
The effects of somatostatin on gastric motility and nutrient absorption from a mixed meal were evaluated in conscious rhesus monkeys (M. mulatta). Continuous saline or somatostatin (0.8 μg/kg × min) infusions were carried out prior to and for 2 hr following an intragastric infusion of a complete liquid diet trace-labeled with3H-3-glucose and3H-9, 10-triolein. Gastric motility was assessed from recordings of gastric pressure and from extraluminal strain gauges. Intravenous somatostatin did not alter gastric motility or the rate of absorption of the labeled glucose; lipid absorption, however, was markedly impaired.