Reversible photoregulation of helical structures in short peptides under indoor lighting/dark conditions.
Reversible photoregulation of helical structures in short peptides under indoor lighting/dark conditions.
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DOI：
10.1021/ol0526524
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发表时间：
2006-01
期刊：
影响因子：
5.2
通讯作者：
K. Fujimoto;M. Amano;Yohei Horibe;M. Inouye
中科院分区：
文献类型：
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作者：
K. Fujimoto;M. Amano;Yohei Horibe;M. Inouye
[反应：开发了一种具有螺吡喃骨架的光致变色交联剂，用于短肽中螺旋结构的可逆光调节。交联肽的螺旋含量可以通过室温下的环境光和黑暗条件来调节。螺旋内容物的这种转换可以重复几次而基本上不损失任何活性。
[reaction: see text] A photochromic cross-linking agent with a spiropyran skeleton was developed for the reversible photoregulation of helical structures in short peptides. The helical contents of the cross-linked peptides could be regulated by ambient light and dark conditions at room temperature. This switching of the helical contents could be repeated several times without substantial loss of any activity.