Cancer prevalence in Israeli men and women with schizophrenia
Cancer prevalence in Israeli men and women with schizophrenia
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DOI：
10.1016/j.psychres.2017.07.082
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发表时间：
2017-12-01
影响因子：
11.3
通讯作者：
Munitz, Hanan
中科院分区：
文献类型：
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作者：
Agay, Nirit;Flaks-Manov, Natalie;Munitz, Hanan
这项横断面研究的目的是比较精神分裂症患者与非精神分裂症人群的癌症患病率。研究人群包括25至74岁的Clalit Health Services成员，所有数据均来自患者的电子健康记录。在2，060，314名参与研究的成员中，有32，748人被诊断为精神分裂症。患有和不患有精神分裂症的女性的癌症患病率分别为每10，000人491人和每10，000人439人;在男性中，癌症患病率分别为每10，000人226人和每10，000人296人。与没有精神分裂症的男性相比，精神分裂症男性中所有类型癌症的年龄调整患病率显着降低;特别是，与没有精神分裂症的男性相比，精神分裂症男性的前列腺癌和“其他”类别癌症的发病率较低。精神分裂症男性癌症发病率的降低可能反映了某些癌症类型的诊断不足，这可能是由于医疗照顾不足。应努力改进甄别制度。
The aim of this cross-sectional study was to compare cancer prevalence rates among patients with schizophrenia to those of the non-schizophrenia population. The study population included members of Clalit Health Services aged 25 to 74 years and all data was taken from patients' electronic health records. Of the 2,060,314 members who were included in the study, 32,748 had a diagnosis of schizophrenia. Cancer prevalence rates in women with and without schizophrenia were 491 per 10,000 and 439 per 10,000, respectively; in men, cancer prevalence rates were 226 per 10,000 and 296 per 10,000, respectively. The age-adjusted prevalence rate of all-type cancer was significantly lower among men with schizophrenia, compared to men without schizophrenia; specifically, men with schizophrenia had a lower rate of prostate cancer, and of cancers in the "other" category, compared to men without schizophrenia. Reduced cancer rates in men with schizophrenia may reflect under diagnosis of some cancer types, likely due to insufficient medical attention. An effort to improve screening regimes should be made.