Resting frontal gamma power at 16, 24 and 36 months predicts individual differences in language and cognition at 4 and 5 years
Resting frontal gamma power at 16, 24 and 36 months predicts individual differences in language and cognition at 4 and 5 years
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DOI：
10.1016/j.bbr.2011.01.048
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发表时间：
2011-07-07
影响因子：
2.7
通讯作者：
Benasich, April A.
中科院分区：
文献类型：
--
作者：
Gou, Zhenkun;Choudhury, Naseem;Benasich, April A.
伽马活动与各种不同的认知过程有关，并以短暂和持久的形式存在。在所有研究中，不同的大脑区域被认为有助于伽马活动。多项研究表明，伽马振荡的功能可能与早期感觉信息与相关自上而下过程的时间绑定有关。鉴于这一假设，我们预计伽马振荡有助于促进认知和语言系统发展的一般大脑机制。本研究旨在探讨语言和认知习得关键点（16、24和36个月）的静息态皮层γ功率密度与4岁和5岁时的认知和语言输出之间的预测关系，发现24和36个月的γ功率与以后的语言成绩显著相关，尤其是非单词重复。此外，16个月、24个月和36个月的伽马值与4年的PLS-3和CELF-P句子结构得分显著相关。尽管这里报道的相关性并不能反映早期静息伽马值对后期语言结果的直接因果关系，在关键的发展时期，在伽马范围内产生更高功率的能力可能是注意力更好调节的指标，并允许更容易进入工作状态。记忆，从而为全面发展提供了优势，特别是在语言领域。此外，在这些能力仍然涌现的时候测量这些能力可能会更好地预测以后的结果。(C)2011爱思唯尔有限公司版权所有。
Gamma activity has been linked to a variety of different cognitive processes and exists in both transient and persistent forms. Across studies, different brain regions have been suggested to contribute to gamma activity. Multiple studies have shown that the function of gamma oscillations may be related to temporal binding of early sensory information to relevant top-down processes. Given this hypothesis, we expected gamma oscillations to subserve general brain mechanisms that contribute to the development of cognitive and linguistic systems. The present study aims to examine the predictive relations between resting-state cortical gamma power density at a critical point in language and cognitive acquisition (i.e. 16,24 and 36 months), and cognitive and language output at ages 4 and 5 years.Our findings show that both 24- and 36-month gamma power are significantly correlated with later language scores, notably Non-Word Repetition. Further, 16-, 24- and 36-month gamma were all significantly correlated with 4-year PLS-3 and CELF-P sentence structure scores.Although associations reported here do not reflect a direct cause and effect of early resting gamma power on later language outcomes, capacity to generate higher power in the gamma range at crucial developmental periods may index better modulation of attention and allow easier access to working memory, thus providing an advantage for overall development, particularly in the linguistic domain. Moreover, measuring abilities at times when these abilities are still emergent may allow better prediction of later outcomes. (C) 2011 Elsevier B.V. All rights reserved.