Sleep duration and mortality in the elderly: a systematic review with meta-analysis.
Sleep duration and mortality in the elderly: a systematic review with meta-analysis.
复制标题
DOI：
10.1136/bmjopen-2015-008119
复制
发表时间：
2016-02-17
期刊：
影响因子：
2.9
通讯作者：
Fuchs SC
中科院分区：
文献类型：
--
作者：
da Silva AA;de Mello RG;Schaan CW;Fuchs FD;Redline S;Fuchs SC
本研究的目的是评估老年人睡眠时间长短与全因和心血管死亡率之间的关系。基于人群的队列研究的系统综述和荟萃分析。文章从国际和国家电子数据库中检索。1980年至2015年期间，在PubMed，EMBASE，LILACS（拉丁美洲和加勒比健康科学文献），IBECS（西班牙健康科学文献索引）和CAPES（博士论文库）中确定了研究。符合所有标准的研究是合格的：年龄在60岁或以上的参与者，评估睡眠时间为24小时，夜间或白天睡眠，评估全因或特定原因的死亡率，对代表性样本进行的基于人群的队列研究。 没有语言限制，以摘要形式发表的研究被排除。使用综合荟萃分析软件（V.3.3.070）分析数据，并使用随机效应模型计算汇总估计值（相对风险（RR），95% CI）。通过Cochran’s Q和I2统计量分别评估异质性和一致性，并进行敏感性分析。全因和心血管死亡率。总体而言，选择了27项队列研究，包括>70 000名老年人，随访时间为3.4至35年。 在汇总分析中，与参考类别相比，睡眠时间长和睡眠时间短与全因死亡率增加相关（RR 1.33; 95%CI 1.24至1.43和RR 1.07; 95%CI 1.03至1.11）。对于心血管死亡率，长时间睡眠的合并相对风险为1.43（95%CI 1.15至1.78），短时间睡眠的合并相对风险为1.18（95%CI 0.76至1.84）。白天小睡≥30 min与全因死亡风险相关（RR 1.27; 95% CI 1.08 - 1.49），与白天无睡眠相比，但睡眠时间较长（≥2.0 h）与全因死亡风险无关（RR 1.34; 95% CI 1.95 - 1.90）。 在老年人中，睡眠时间长短与全因死亡风险增加有关。长时间睡眠与心血管死亡率有关。
The purpose of our study was to evaluate the association between short and long sleep duration and all-cause and cardiovascular mortality among elderly individuals. Systematic review and meta-analysis of population-based cohort studies. Articles were retrieved from international and national electronic databases. Studies were identified in PubMed, EMBASE, LILACS (Latin American and Caribbean Health Sciences Literature), IBECS (Bibliographic Index on Health Sciences from Spain) and CAPES (PhD thesis repository) between 1980 and 2015. Studies which met all criteria were eligible: participants aged 60 years or over, assessment of sleep duration as 24 h, nighttime or daytime sleep, evaluation of all-cause or cause-specific mortality, population-based cohort studies conducted on representative samples. There was no language restriction and studies published as abstracts were excluded. Data were analysed using the Comprehensive Meta-Analysis software (V.3.3.070), and summary estimates (relative risk (RR), 95% CI) were calculated using a random effects model. Heterogeneity and consistency were evaluated through Cochran's Q and the I2 statistics, respectively, and sensitivity analyses were conducted. All-cause and cardiovascular mortality. Overall, 27 cohort studies were selected, comprising >70 000 elderly individuals, and followed up from 3.4 to 35 years. In the pooled analysis, long and short sleep duration were associated with increased all-cause mortality (RR 1.33; 95% CI 1.24 to 1.43 and RR 1.07; 95% CI 1.03 to 1.11, respectively), compared with the reference category. For cardiovascular mortality, the pooled relative risks were 1.43 (95% CI 1.15 to 1.78) for long sleep, and 1.18 (95% CI 0.76 to 1.84) for short sleep. Daytime napping ≥30 min was associated with risk of all-cause mortality (RR 1.27; 95% CI 1.08 to 1.49), compared with no daytime sleep, but longer sleep duration (≥2.0 h) was not (RR 1.34; 95% CI 1.95 to 1.90). Among elderly individuals, long and short sleep duration are associated with increased risk for all-cause mortality. Long sleep duration is associated with cardiovascular mortality.