Anatomical location of normal skin flora.
Anatomical location of normal skin flora.
复制标题
正常皮肤菌群的解剖位置。
DOI：
10.1001/archderm.1970.04000020015004
复制
发表时间：
1970
影响因子：
--
通讯作者：
W. Wilborn
中科院分区：
文献类型：
--
作者：
L. Montes;W. Wilborn
进行了一项调查，以可视化细菌在正常人类皮肤中的位置。正常皮肤样本取自前额、后颈部、上背部、头皮、前臂前部、腹部、耻骨区、腿部和趾蹼。闭塞后的皮肤，小的未发炎的粉刺和三角间的标本也被使用。在电子显微镜下，根据Ryter-Kellenberger， Caulfield或Hess技术固定每个标本的一部分。每个标本的剩余部分进行光学显微镜处理。一些细菌位于皮肤表面和角质层表面细胞下。在后一地点偶见小菌落。毛囊的开口含有许多微生物，这些微生物通常与皮脂有关。闭塞后正常皮肤细菌数量增加。粉刺中的细菌比研究过的任何样本都要多。
An investigation was undertaken to visualize the location of bacteria in normal human skin. Samples of normal skin were used from forehead, posterior neck, upper back, scalp, anterior forearm, abdomen, pubic area, leg, and toewebs. Skin following occlusion, small uninflamed comedones, and specimens of intertrigo were also employed. For electron microscopy, part of each specimen was fixed according to the technique of Ryter-Kellenberger, Caulfield, or Hess. The remainder of each specimen was processed for light microscopy. Some bacteria were located on the skin surface and beneath superficial cells of the stratum corneum. Microcolonies were occasionally seen in the latter location. Openings of hair follicles contained numerous microorganisms which were often associated with sebum. Bacterial population increased in normal skin after occlusion. Comedones displayed more bacteria than any sample studied.