Malignant adenomyoepithelioma of the breast with matrix production may be compatible with one variant form of matrix-producing carcinoma: A case report
Malignant adenomyoepithelioma of the breast with matrix production may be compatible with one variant form of matrix-producing carcinoma: A case report
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DOI：
10.1016/j.prp.2007.04.004
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发表时间：
2007-01-01
影响因子：
2.8
通讯作者：
Yatabe, Yasushi
中科院分区：
文献类型：
--
作者：
Oka, Kuniyuki;Sando, Norimasa;Yatabe, Yasushi
我们检查了一位77岁的妇女谁患有左乳房肿瘤。她在68岁时因浸润性导管癌接受了右乳房切除术，在74岁时因粘液癌接受了直肠切除术。左侧乳房肿瘤的尺寸为3.8 x 2.5 x 1.6 cm。肿瘤细胞由非典型上皮细胞和肌上皮细胞组成。前者细胞呈多边形，体积较大。它们位于肿瘤周围，呈导管状排列，表达细胞角蛋白、S-100蛋白、maspin和MIC 2。后者细胞由暗细胞和星状细胞组成，暗细胞以导管周围模式增殖，星状细胞位于肿瘤中心。它们侵入软骨粘液样组织，并以花边样模式增殖。非典型肌上皮细胞表达波形蛋白、S-100蛋白、maspin和MIC 2。我们的结论是恶性腺肌上皮瘤的乳腺与基质生产可能是兼容的一种变异形式的基质生产癌。(c)2007年，Elsevier GmbH。All rights reserved.
We examined a 77-year-old woman who suffered from a left breast tumor. She had undergone right mastectomy for invasive ductal carcinoma at 68 years of age, and rectal resection for mucinous carcinoma at the age of 74 years. The left breast tumor measured 3.8 x 2.5 x 1.6cm. Neoplastic cells consisted of atypical epithelial and myoepithelial cells. The former cells were polygonal and large. They were located in the periphery of the tumor, arranged in a ductal pattern, and expressed cytokeratins, S-100 protein, maspin, and MIC2. The latter cells were composed of dark cells which proliferated in a periductal pattern, and stellate cells which were located in the center of the tumor. They invaded the chondromyxoid tissues, and proliferated in a lace-like pattern. Atypical myoepithelial cells expressed vimentin, S-100 protein, maspin, and MIC2. We conclude that malignant adenomyoepithelioma of the breast with matrix production might be compatible with a variant form of matrix-producing carcinoma. (c) 2007 Elsevier GmbH. All rights reserved.