Crossed Cerebellar Diaschisis in Ischemic Stroke: A Study of Regional Cerebral Blood Flow by 133Xe Inhalation and Single Photon Emission Computerized Tomography
Crossed Cerebellar Diaschisis in Ischemic Stroke: A Study of Regional Cerebral Blood Flow by 133Xe Inhalation and Single Photon Emission Computerized Tomography
复制标题
缺血性中风中的交叉小脑联系不全：133Xe 吸入和单光子发射计算机断层扫描对局部脑血流的研究
DOI：
10.1038/jcbfm.1984.32
复制
发表时间：
1984
影响因子：
6.3
通讯作者：
N. Lassen
中科院分区：
文献类型：
--
作者：
G. Meneghetti;S. Vorstrup;B. Mickey;H. Lindewald;N. Lassen
通过吸入133 Xe和快速旋转单光子发射计算机断层扫描仪对12名中风患者进行了70次CBF测量。在急性期以及2个月和6个月随访访视时，每隔一天测量一次CBF。持续对侧小脑血流抑制是明显的，在5例严重的半球低流量区，这与计算机断层扫描上的大，低密度病变。在第六例小而深的梗死患者中，观察到短暂的交叉小脑低血流，而临床症状持续存在。从这一系列研究中可以得出结论，交叉性小脑神经联系不能是完全性卒中的常见发现。它可能是由皮质桥脑通路的断开引起的，这种断开往往会持续下去。事实上，这种现象比梗塞半球中风相关的CBF变化变化要少，梗塞半球经常出现一段相对充血期。
Seventy measurements of CBF were performed in 12 stroke patients by 133Xe inhalation and a rapidly rotating single photon emission computerized tomograph. CBF was measured every other day during the acute phase and at 2- and 6-month follow-up visits. A persistent contralateral cerebellar blood flow depression was evident in five patients with severe hemispheric low flow areas, which correlated with large, hypodense lesions on the computerized tomographic scan. In a sixth patient with a small, deep infarct, a transient crossed cerebellar low flow was observed, while the clinical symptoms persisted. It is concluded from this serial study that crossed cerebellar diaschisis is a common finding in completed stroke. It is probably caused by disconnection of the corticopontine pathways, a disconnection that tends to persist. The phenomenon is in fact less variable than the stroke-related CBF changes in the infarcted hemisphere, in which a period of relative hyperemia is frequently seen.