Postviral Complications: Bacterial Pneumonia.
Postviral Complications: Bacterial Pneumonia.
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DOI：
10.1016/j.ccm.2016.11.006
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发表时间：
2017-03
影响因子：
5.7
通讯作者：
Deng JC
中科院分区：
文献类型：
--
作者：
Prasso JE;Deng JC
病毒性呼吸道感染后继发细菌性肺炎仍然是发病率和死亡率的重要来源。易感性是由多种病毒和细菌因素以及与宿主免疫系统的复杂相互作用介导的。预防和治疗策略分别仅限于流感疫苗接种和抗生素/抗病毒药物。迫切需要新的方法来识别继发性细菌性肺炎风险增加的流感患者。考虑到进一步流行病的威胁和这些病毒的流行率上升，有必要对该疾病的免疫机制进行更多研究，以期发现新的潜在疗法。
Secondary bacterial pneumonia after viral respiratory infection remains a significant source of morbidity and mortality. Susceptibility is mediated by a variety of viral and bacterial factors, and complex interactions with the host immune system. Prevention and treatment strategies are limited to influenza vaccination and antibiotics/antivirals respectively. Novel approaches to identifying the individuals with influenza who are at increased risk for secondary bacterial pneumonias are urgently needed. Given the threat of further pandemics and the heightened prevalence of these viruses, more research into the immunologic mechanisms of this disease is warranted with the hope of discovering new potential therapies.