Rational use of the EAC real-time quantitative PCR protocol in chronic myelogenous leukemia: report of three false-negative cases at diagnosis

Rational use of the EAC real-time quantitative PCR protocol in chronic myelogenous leukemia: report of three false-negative cases at diagnosis
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EAC实时定量PCR方案在慢性粒细胞白血病中的合理应用:三例诊断假阴性报告

DOI:
10.1038/sj.leu.2404174
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发表时间:
2006
期刊:
影响因子:
11.4
通讯作者:
P. Heimann
P. Heimann
中科院分区:
医学1区
文献类型:
--
作者:
B. Dessars;H. Housni;F. Lambert;A. Kentos;P. Heimann

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缩略语:BM,骨髓; Cyto,细胞遗传学结果; Dim,抗原表达,染色强度在同种型对照的1 log内;。N/A,结果不可用; Neg,抗原未表达; Pos,抗原表达; TCR,T细胞受体异源二聚体表达; Tg PCR,使用TCR g链基因特异性引物的聚合酶链反应; Vb flow,使用特异性TCR-Vb家族抗体的流式细胞术方法。a荧光原位杂交法。
Abbreviations: BM, bone marrow; Cyto, cytogenetic findings; Dim, antigen expressed with staining intensity within 1log of isotype control;. N/A, results not available; Neg, antigen not expressed; Pos, antigen expressed; TCR, T-cell receptor heterodimer expressed; Tg PCR, polymerase chain reaction using TCR g chain gene specific primers; Vb flow, flow cytometric method using antibodies to specific TCR-Vb families. aBy fluorescence in situ hybridization.