Community-associated methicillin-resistant Staphylococcus aureus infections at an Army training installation
Community-associated methicillin-resistant Staphylococcus aureus infections at an Army training installation
复制标题
DOI：
10.1017/s0950268810000142
复制
发表时间：
2010-05-01
影响因子：
4.2
通讯作者：
Jordan, N. N.
中科院分区：
文献类型：
--
作者：
Morrison-Rodriguez, S. M.;Pacha, L. A.;Jordan, N. N.
为了评估社区相关耐甲氧西林金黄色葡萄球菌（CA-M RSA）在高危人群中的负担，计算了2002-2007日历年美国格鲁吉亚本宁堡（Fort Benning）驻扎的服务人员/受训人员中实验室确认的M RSA的月发病率，这些人员在感染前30天未住院或手术。临床管理和抗生素敏感性模式也进行了评价。到2007年，67%的S。金黄色葡萄球菌菌株是M RSA，其中82%是社区相关的，主要是在受训人员中。总共确定了3531例CA-MRSA感染。发病率似乎是季节性的，2005年达到高峰，为每1 000名士兵42例，此后发病率一直保持在每1 000名士兵35例以上。记录了有效抗生素处方的增加。克林霉素、环丙沙星和左氧氟沙星的敏感性从2002年到2007年分别下降了6%、17%和14%。观察到的CA-M RSA的持续高流行率突出表明，需要在军事训练设施中采取更警惕的基于人口的反措施。
To assess the burden of community-associated methicillin-resistant Staphylococcus aureus (CA-M RSA) in a high-risk population, the monthly incidence of laboratory-confirmed M RSA in service members/trainees stationed at Fort Benning, Georgia, USA without hospitalization or surgery documented 30 days prior to infection was calculated for calendar years 2002-2007. Clinical management and antibiotic susceptibility patterns were also evaluated. By 2007, 67% of S. aureus strains were M RSA, and 82% of these were community-associated, primarily in trainees. In total, 3531 CA-MRSA infections were identified. Rates appeared to be seasonal, peaking at 42 cases/1000 soldiers in 2005, with rates remaining above 35/1000 soldiers thereafter. Increased prescription of effective antibiotics was documented. Susceptibility to clindamycin, ciprofloxacin, and levofloxacin decreased from 2002 to 2007 by 6%, 17%, and 14%, respectively. The sustained high prevalence of CA-M RSA observed highlights the need for more vigilant population-based counter-measures at military training installations.