Pulmonary tuberculosis among health care workers at two designated DOTS Centers in urban city of Ibadan, Nigeria
Pulmonary tuberculosis among health care workers at two designated DOTS Centers in urban city of Ibadan, Nigeria
复制标题
尼日利亚伊巴丹市两个指定 DOTS 中心的医护人员患有肺结核
DOI：
--
复制
发表时间：
2011
期刊：
影响因子：
--
通讯作者：
O. Adebiyi
中科院分区：
文献类型：
--
作者：
A. O. Kehinde;A. Baba;Bakare Ra;O. Ige;C. F. Gbadeyanka;O. Adebiyi
背景和目标：在包括尼日利亚在内的许多撒哈拉以南非洲国家，结核病感染控制干预措施没有得到常规实施。本研究旨在确定尼日利亚伊巴丹两个指定DOTS中心的卫生保健工作者（HCW）中职业获得性肺结核（PTB）的程度。研究方法：在位于尼日利亚伊巴丹的大学学院医院和杰里科胸科医院进行了为期一年的描述性研究（2008年1月至12月）。一个预先测试的问卷被用来获得社会人口学数据和其他相关信息的主题。从每例受试者中采集3份痰液样本。使用Zeihl-Neelsen（Z-N）染色剂对其进行处理。将其中一种痰液在改良的Ogawa卵培养基上培养，在37°C下孵育6周。经Z-N染色和生化检查证实为结核分枝杆菌。结果：共271例受试者，男性117例（43.2%），女性154例（56.8%）。9例（3.3%）痰抗酸杆菌（AFB）阳性，6例（2.2%）痰培养阳性。细菌污染率为百分之一点八，值得注意的是，所有六个细菌阳性样本均来自男性，而没有一个来自女性。大约一半的AFB阳性样本来自在工作单位工作了五年的受试者。AFB阳性者8例，年龄21-50岁，学生7例。解释和结论：研究表明，职业性肺结核在伊巴丹是真实的。需要进一步研究，以确定和解决这一问题的严重性。
Background & objectives: Tuberculosis (TB) infection control interventions are not routinely implemented in many Sub-Saharan African countries including Nigeria. This study was carried out to ascertain the magnitude of occupationally-acquired pulmonary TB (PTB) among health care workers (HCWs) at two designated DOTS centers in Ibadan, Nigeria. Methods: One year descriptive study (January-December 2008) was carried out at the University College Hospital and Jericho Chest Hospital, both located in Ibadan, Nigeria. A pre-tested questionnaire was used to obtain socio-demographic data and other relevant information from the subjects. Three sputum samples were collected from each subject. This was processed using Zeihl-Neelsen (Z-N) stains. One of the sputum was cultured on modified Ogawa egg medium incubated at 37°C for six weeks. Mycobacterium tuberculosis was confirmed by repeat Z-N staining and biochemical tests. Results: A total of 271 subjects, 117 (43.2%) males and 154 (56.8%) females were studied. Nine (3.3%) had their sputum positive for acid fast bacilli (AFB) while six (2.2%) were positive for culture. The culture contamination rate was 1.8 per cent. Significantly, all the six culture positive samples were from males while none was obtained from their female counterparts. About half of the AFB positive samples were from subjects who have spent five years in their working units. Eight AFB positive cases were from 21-50 yr age group while students accounted for seven AFB positive cases. Interpretation & conclusions: The study shows that occupationally-acquired PTB is real in Ibadan. Further studies are needed to ascertain and address the magnitude of the problem.