The mitochondrial oxidation resistance protein AtOXR2 increases plant biomass and tolerance to oxidative stress
The mitochondrial oxidation resistance protein AtOXR2 increases plant biomass and tolerance to oxidative stress
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DOI：
10.1093/jxb/erz147
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发表时间：
2019-06-01
影响因子：
6.9
通讯作者：
Welchen, Elina
中科院分区：
文献类型：
--
作者：
Colombatti, Francisco;Mencia, Regina;Welchen, Elina
本研究证实了植物中存在抗氧化蛋白家族。拟南芥中有六个OXR成员含有高度保守的TLDc结构域，这是该真核蛋白家族的特征。AtOXR 2是一种线粒体蛋白，能够减轻酵母oxr 1突变体的应激敏感性。它是由氧化应激诱导的，其在拟南芥中的过表达（oeOXR2）增加了叶片抗坏血酸，光合作用，生物量和种子产量，以及赋予对甲基紫精，抗霉素A和高光强度的耐受性。oeOXR2植物也表现出较高的阿坝含量，阿坝敏感性的变化，和修改的阿坝和应力调节基因的表达。虽然oxr2突变体具有与野生型相似的芽表型，但它们表现出对胁迫的敏感性增加。我们提出，通过影响活性氧（ROS）的水平，AtOXR 2提高了光合作用的效率，并增强了对增加氧化应激的环境挑战的基础耐受性，从而改善了植物生长和生物量生产。
This study demonstrates the existence of the oxidation resistance (OXR) protein family in plants. There are six OXR members in Arabidopsis that contain the highly conserved TLDc domain that is characteristic of this eukaryotic protein family. AtOXR2 is a mitochondrial protein able to alleviate the stress sensitivity of a yeast oxr1 mutant. It was induced by oxidative stress and its overexpression in Arabidopsis (oeOXR2) increased leaf ascorbate, photosynthesis, biomass, and seed production, as well as conferring tolerance to methyl viologen, antimycin A, and high light intensities. The oeOXR2 plants also showed higher ABA content, changes in ABA sensitivity, and modified expression of ABA- and stress-regulated genes. While the oxr2 mutants had a similar shoot phenotype to the wild-type, they exhibited increased sensitivity to stress. We propose that by influencing the levels of reactive oxygen species (ROS), AtOXR2 improves the efficiency of photosynthesis and elicits basal tolerance to environmental challenges that increase oxidative stress, allowing improved plant growth and biomass production.