Long-term results after curative resection for carcinoma of the gallbladder

Long-term results after curative resection for carcinoma of the gallbladder
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DOI:
10.1016/s0002-9610(97)00269-9
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发表时间:
1998-02-01
影响因子:
3
通讯作者:
Fagniez, PL
Fagniez, PL
中科院分区:
医学3区
文献类型:
--
作者:
Benoist, S;Panis, Y;Fagniez, PL

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背景:胆囊癌的手术治疗存在争议,尤其是根治性切除的适应证。本研究的目的是评估胆囊癌的手术治疗结果,特别是其组织学扩散程度。方法:来自法国 25 个中心的 86 名患者接受了切除术并被纳入本研究。他们包括 65 名女性和 21 名男性(平均年龄 65 +/- 21 岁)。切除术包括21例患者的根治性切除术(部分肝切除、区域淋巴结清扫和胆总管切除术)和65例的单纯胆囊切除术。结果:术后死亡3例(3.5%)。平均随访时间为 25 +/- 24 个月。总体 5 年精算生存率为 26%。接受根治性切除的患者的 5 年精算生存率为 27%。 8 名有淋巴结转移的患者的 B 年生存率为 0%,而 13 名无淋巴结转移的患者的 B 年生存率为 43%(P
BACKGROUND: The surgical management of gallbladder carcinoma is controversial, especially as regards the indications for radical resection. The aim of this study was to evaluate the results of surgical treatment for gallbladder carcinoma with special reference to the extent of its histological spread.METHODS: Eighty-six patients from 25 French centers underwent resection for cure and were included in this study. They comprised 65 women and 21 men (mean age 65 +/- 21 years). Resection included radical resection in 21 patients (partial hepatectomy, regional lymphadenectomy, and common bile duct resection) and simple cholecystectomy in 65.RESULTS: There were 3 postoperative deaths (3.5%). The mean follow-up period was 25 +/- 24 months. The overall 5-year actuarial survival rate was 26%. The 5-year actuarial survival rate was 27% for patients who had radical resection. Eight patients with nodal metastasis had a B-year survival rate of 0%, but the rate for 13 patients without such metastasis was 43% (P