FUNCTIONAL-SIGNIFICANCE OF THE MU RHYTHM OF HUMAN CORTEX - AN ELECTROPHYSIOLOGIC STUDY WITH SUBDURAL ELECTRODES
FUNCTIONAL-SIGNIFICANCE OF THE MU RHYTHM OF HUMAN CORTEX - AN ELECTROPHYSIOLOGIC STUDY WITH SUBDURAL ELECTRODES
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DOI：
10.1016/0013-4694(93)90114-b
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发表时间：
1993-09-01
期刊：
影响因子：
--
通讯作者：
WEBBER, R
中科院分区：
文献类型：
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作者：
ARROYO, S;LESSER, RP;WEBBER, R
Mu节律的存在及其一般的解剖和生理关系是众所周知的。然而，关于其解剖学和生理学特异性的细节方面的数据很少。我们在9例顽固性癫痫患者中植入了额颞部硬膜下电极格栅，以方便手术治疗。通过电刺激，在感觉运动皮质上方的5-16个电极上观察到7-11赫兹的皮层MU节律。MU节律被对侧面部和手臂运动、对侧手臂被动运动和同侧手臂运动所阻断。在某一特定部位阻断MU的身体区域运动与在同一部位受到刺激影响的身体区域之间存在对应关系。功率谱分析显示，所有频段的功率都有所下降。这在14-100赫兹频段没有那么明显，导致与运动相关的高频功率的相对增加。我们得出结论，Mu节律的存在和阻断都是记录它的皮层的躯体表征特有的。它的功能意义可能类似于其他感官节律，如枕骨阿尔法节律。
The existence of the mu rhythm and its general anatomical and physiological relationships are well known. There are few data, however, regarding the details of its anatomical and physiological specificity. We implanted fronto-temporal subdural electrode grids in 9 patients with intractable epilepsy to facilitate their surgical management. A 7-11 Hz cortical mu rhythm was observed in 5-16 electrodes located over the sensorimotor cortex as mapped by electrical stimulation. The mu rhythm was blocked by contralateral face and arm movements, passive movements of contralateral arm, and by ipsilateral arm movements. There was correspondence between the body area movement of which blocked the mu at a given site and the body region that was affected by stimulation at the same site. Power spectral analysis showed an overall decrease in power in all frequency bands. This was less prominent in the 14-100 Hz band resulting in a relative increase in high frequency power in association with movement.We conclude that both the presence and blocking of mu rhythm are specific to the somatic representation of the cortex from which it is recorded. Its functional significance may be similar to other sensory rhythms like the occipital alpha rhythm.