Polypropylene-based membrane adsorbers via photo-initiated graft copolymerization: Optimizing separation performance by preparation conditions
Polypropylene-based membrane adsorbers via photo-initiated graft copolymerization: Optimizing separation performance by preparation conditions
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DOI：
10.1016/j.memsci.2007.12.027
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发表时间：
2008-03
影响因子：
9.5
通讯作者：
A. H. M. Yusof;M. Ulbricht
中科院分区：
文献类型：
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作者：
A. H. M. Yusof;M. Ulbricht
通过受控的表面功能化可以非常有效地制备新型分离膜。采用最近开发的光引发剂二苯甲酮（BP）的包埋方法进行光引发表面选择性接枝共聚，并以丙烯酸（AA）为功能单体在聚丙烯膜孔表面获得弱阳离子交换聚合物刷结构。 AA 与“稀释剂”单体丙烯酰胺 (AAm) 和“交联剂”单体亚甲基双丙烯酰胺 (MBAA) 进行共聚，以获得接枝层的变化。使用 FTIR-ATR 光谱法进行接枝共聚物组成分析。通过测量低 pH 值和高 pH 值以及不同盐浓度下的膜渗透性、模型蛋白（溶菌酶）的可逆结合、膜色谱条件下无意的 pH 瞬变以及系统分散分析的突破曲线来完成性能表征。这项研究最重要的结果是，接枝层内的化学交联与线性接枝聚合物的官能团数量大致相同，可以显着改善多孔吸附剂的性能，因为动态蛋白质结合能力可以增加，膜渗透性显着增加，并且它对洗脱液pH和盐浓度变化的敏感性大大降低，因此膜内溶质的分散度降低，如明显更尖锐的突破曲线所示。
Preparation of novel separation membranes can be done very efficiently with controlled surface functionalization. Photo-initiated surface-selective graft copolymerization was performed using a recently developed entrapping method for the photo-initiator benzophenone (BP), and weak cation-exchange polymer brush structures on polypropylene membrane pore surfaces were obtained using acrylic acid (AA) as functional monomer. Copolymerization of AA with “diluent” monomer acrylamide (AAm) and “cross-linker” monomer methylene bisacrylamide (MBAA) were done for variations of the grafted layer. Graft copolymer composition analysis had been performed using FTIR-ATR spectroscopy. Performance characterizations had been done by measurements of membrane permeability at low and high pH as well as at different salt concentrations, by reversible binding of a model protein (lysozyme), by inadvertent pH transient under membrane chromatography conditions and by breakthrough curves for system dispersion analysis. The most important result of this study is that chemical cross-linking within grafted layers with about the same amount of functional groups than those from linear grafted polymer leads to a significant improvement of porous adsorber performance because the dynamic protein binding capacity can be increased, the membrane permeability is significantly increased and it's sensitivity to changes in eluent pH and salt concentration is much decreased, and consequently the solute dispersion within the membrane is reduced as indicated by significantly sharper break-through curves.