CT-Based Risk Stratification for Intensive Care Need and Survival in COVID-19 Patients-A Simple Solution.
CT-Based Risk Stratification for Intensive Care Need and Survival in COVID-19 Patients-A Simple Solution.
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DOI：
10.3390/diagnostics11091616
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发表时间：
2021-09-04
期刊：
影响因子：
--
通讯作者：
Böning G
中科院分区：
文献类型：
--
作者：
Hosse C;Büttner L;Fleckenstein FN;Hamper CM;Jonczyk M;Scholz O;Aigner A;Böning G
我们评估了一种简单的半定量（SSQ）方法，用于确定COVID-19患者计算机断层扫描（CT）扫描中的肺部受累。采用SSQ方法和主观评估首次可用CT的肺部受累程度。我们确定了需要有创通气、重症监护室（ICU）入院和感染后死亡时间的风险因素。此外，还评估了这两种方法的诊断性能。使用SSQ方法，发现受累肺面积增加10%会显著增加需要ICU治疗的风险，比值比（OR）为1.68，需要有创通气的风险为1.35。男性、年龄和既往存在的慢性肺病也与较高的风险相关。受影响的肺面积越大，死亡的瞬时风险越高（风险比（HR）为1.11），与其他风险因素无关。SSQ测量略上级主观方法，ICU治疗需要的AUC为73.5%，有创通气为72.7%。在COVID-19患者的第一次可用CT扫描中对受影响肺部进行SSQ评估，可能有助于早期识别需要ICU治疗、有创通气或死亡的风险较高的患者。
We evaluated a simple semi-quantitative (SSQ) method for determining pulmonary involvement in computed tomography (CT) scans of COVID-19 patients. The extent of lung involvement in the first available CT was assessed with the SSQ method and subjectively. We identified risk factors for the need of invasive ventilation, intensive care unit (ICU) admission and for time to death after infection. Additionally, the diagnostic performance of both methods was evaluated. With the SSQ method, a 10% increase in the affected lung area was found to significantly increase the risk for need of ICU treatment with an odds ratio (OR) of 1.68 and for invasive ventilation with an OR of 1.35. Male sex, age, and pre-existing chronic lung disease were also associated with higher risks. A larger affected lung area was associated with a higher instantaneous risk of dying (hazard ratio (HR) of 1.11) independently of other risk factors. SSQ measurement was slightly superior to the subjective approach with an AUC of 73.5% for need of ICU treatment and 72.7% for invasive ventilation. SSQ assessment of the affected lung in the first available CT scans of COVID-19 patients may support early identification of those with higher risks for need of ICU treatment, invasive ventilation, or death.
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影响因子：
19.7
作者：
Kanne JP;Bai H;Bernheim A;Chung M;Haramati LB;Kallmes DF;Little BP;Rubin GD;Sverzellati N
通讯作者：
Sverzellati N
影响因子：
3.9
作者：
Di Castelnuovo A;Costanzo S;Antinori A;Berselli N;Blandi L;Bonaccio M;Bruno R;Cauda R;Gialluisi A;Guaraldi G;Menicanti L;Mennuni M;My I;Parruti A;Patti G;Perlini S;Santilli F;Signorelli C;Stefanini GG;Vergori A;Ageno W;Aiello L;Agostoni P;Al Moghazi S;Arboretti R;Aucella F;Barbieri G;Barchitta M;Bartoloni A;Bologna C;Bonfanti P;Caiano L;Carrozzi L;Cascio A;Castiglione G;Chiarito M;Ciccullo A;Cingolani A;Cipollone F;Colomba C;Colombo C;Crosta F;Dalena G;Dal Pra C;Danzi GB;D'Ardes D;de Gaetano Donati K;Di Gennaro F;Di Tano G;D'Offizi G;Filippini T;Maria Fusco F;Gaudiosi C;Gentile I;Gini G;Grandone E;Guarnieri G;Lamanna GLF;Larizza G;Leone A;Lio V;Losito AR;Maccagni G;Maitan S;Mancarella S;Manuele R;Mapelli M;Maragna R;Marra L;Maresca G;Marotta C;Mastroianni F;Mazzitelli M;Mengozzi A;Menichetti F;Milic J;Minutolo F;Molena B;Mussinelli R;Mussini C;Musso M;Odone A;Olivieri M;Pasi E;Perroni A;Petri F;Pinchera B;Pivato CA;Poletti V;Ravaglia C;Rossato M;Rossi M;Sabena A;Salinaro F;Sangiovanni V;Sanrocco C;Scorzolini L;Sgariglia R;Simeone PG;Spinicci M;Trecarichi EM;Veronesi G;Vettor R;Vianello A;Vinceti M;Visconti E;Vocciante L;De Caterina R;Iacoviello L;COVID-19 RISK and Treatments (CORIST) Collaboration
通讯作者：
COVID-19 RISK and Treatments (CORIST) Collaboration
影响因子：
9.6
作者：
Lichtenstein, Daniel A.
通讯作者：
Lichtenstein, Daniel A.
DOI：
10.1148/ryct.2020200075
发表时间：
2020-04-01
期刊：
RADIOLOGY-CARDIOTHORACIC IMAGING
影响因子：
--
作者：
Huang, Lu;Han, Rui;Xia, Liming
通讯作者：
Xia, Liming
影响因子：
168.9
作者：
Huang, Chaolin;Wang, Yeming;Cao, Bin
通讯作者：
Cao, Bin