A role for peroxisomes in photomorphogenesis and development of Arabidopsis
A role for peroxisomes in photomorphogenesis and development of Arabidopsis
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DOI：
10.1126/science.1073633
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发表时间：
2002-07-19
期刊：
影响因子：
56.9
通讯作者：
Chory, J
中科院分区：
文献类型：
--
作者：
Hu, JP;Aguirre, M;Chory, J
核蛋白DET 1是植物光形态建成的一个中心阻遏物。我们已经确定了ted 3中的分子损伤，ted 3是一种主要抑制det 1 -1表型的突变。TED 3编码拟南芥生长所必需的过氧化物酶体蛋白（AtPex 2 p）。发育缺陷和det 1中许多基因的异常表达被ted 3拯救。TED 3还部分抑制另一种多效性去黄化突变体COP 1。因此，过氧化物酶体，其功能在很大程度上仍然是未开发的，发挥了关键作用的负调控的DET 1和COP蛋白的光形态发生途径。
The nuclear protein DET1 is a central repressor of photomorphogenesis in plants. We have identified the molecular lesion in ted3, a mutation that dominantly suppresses the phenotypes of det1-1. TED3 encodes a peroxisomal protein (AtPex2p) essential for Arabidopsis growth. Developmental defects and the abnormal expression of many genes in det1 are rescued by ted3. ted3 also partially suppresses another pleiotropic de-etiolated mutant cop1. Thus, peroxisomes, whose functions are still largely unexplored, play a key role in a photomorphogenetic pathway negatively regulated by the DET1 and COP proteins.