A fully-coupled fluid-structure interaction simulation of cerebral aneurysms
A fully-coupled fluid-structure interaction simulation of cerebral aneurysms
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DOI：
10.1007/s00466-009-0421-4
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发表时间：
2010-06-01
影响因子：
4.1
通讯作者：
Isaksen, J. G.
中科院分区：
文献类型：
--
作者：
Bazilevs, Y.;Hsu, M. -C.;Isaksen, J. G.
本文提出了一种计算血管流体-结构相互作用(FSI)的方法，并将其应用于大脑中动脉分叉的特定患者的动脉瘤模型。回顾了一种完全耦合的流体-结构模拟方法，并介绍了支持患者特定血管FSI分析的网格生成的主要方面。我们研究了血流动力学参数，如壁面剪应力和壁面张力，以检验FSI模型与刚性动脉壁假设的相关性。我们通过四个不同形状和大小的脑动脉瘤患者模型的对比研究，论证了在血管血流模拟中包括柔性壁建模的重要性。
This paper presents a computational vascular fluid-structure interaction (FSI) methodology and its application to patient-specific aneurysm models of the middle cerebral artery bifurcation. A fully coupled fluid-structural simulation approach is reviewed, and main aspects of mesh generation in support of patient-specific vascular FSI analyses are presented. Quantities of hemodynamic interest such as wall shear stress and wall tension are studied to examine the relevance of FSI modeling as compared to the rigid arterial wall assumption. We demonstrate the importance of including the flexible wall modeling in vascular blood flow simulations by performing a comparison study that involves four patient-specific models of cerebral aneurysms varying in shape and size.