Microscopic polyarteritis: presentation, pathology and prognosis.
Microscopic polyarteritis: presentation, pathology and prognosis.
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显微镜下多动脉炎：表现、病理学和预后。
DOI：
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发表时间：
1985
期刊：
影响因子：
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通讯作者：
C. Lockwood
中科院分区：
文献类型：
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作者：
C. Savage;C. Winearls;D. Evans;A. Rees;C. Lockwood
我们已经描述了34例显微镜下多动脉炎，所有的人都有系统性小血管炎的临床证据，主要影响皮肤和肌肉骨骼系统伴有局灶性坏死性肾小球肾炎肾损害。33例患者接受了免疫抑制治疗，包括泼尼松龙、硫唑嘌呤、环磷酰胺和血浆置换的各种组合。五年精算患者和肾脏存活率分别为65%和55%，表明这些患者的积极免疫抑制治疗是有益的。
We have described 34 patients with microscopic polyarteritis, all of whom had clinical evidence of a systemic small vessel vasculitis predominantly affecting the skin and musculoskeletal systems accompanied by a focal necrotising glomerulonephritis with renal impairment. Thirty three patients received immunosuppressive treatment, comprising prednisolone, azathioprine, cyclophosphamide and plasma exchange in various combinations. The five-year actuarial patient and kidney survival rates were 65 and 55 per cent respectively, suggesting that aggressive immunosuppressive therapy in these patients is beneficial.