Childhood cancer in relation to prenatal exposure to atomic-bomb radiation.
Childhood cancer in relation to prenatal exposure to atomic-bomb radiation.
复制标题
儿童癌症与产前暴露于原子弹辐射有关。
DOI：
10.1016/s0140-6736(70)92813-8
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发表时间：
1970
期刊：
影响因子：
168.9
通讯作者：
H. Kato
中科院分区：
文献类型：
--
作者：
S. Jablon;H. Kato
对 1945 年在广岛和长崎出生时暴露于原子弹的 1292 名儿童的青少年癌症经历进行了研究。白血病或其他癌症的死亡率没有显着增加。这一经验与另一组提出的产前 X 射线致癌的具体模型不一致，该模型假设存在线性剂量反应曲线，并估计生命前 10 年中癌症死亡人数为每百万人 rad 572 人。只有大幅修改线性系数的这个值，才能使日本数据与这个模型一致。
The juvenile cancer experience of 1292 children exposed prenatally in 1945 to the atomic bombs in Hiroshima and Nagasaki has been studied. There was no significant excess of mortality from leukæmia or other cancers. This experience is not consistent with the specific model for carcinogenesis as a result of prenatal X-ray, advanced by another group, which postulates a linear dose-response curve and an estimate for cancer deaths in the first ten years of life of 572 per million person-rad. Only by drastically revising this value for the linear coefficient can the Japanese data be made consistent with this model.