Reaction-based colorimetric and fluorogenic signaling of hydrogen sulfide using a 7-nitro-2,1,3-benzoxadiazole-coumarin conjugate
Reaction-based colorimetric and fluorogenic signaling of hydrogen sulfide using a 7-nitro-2,1,3-benzoxadiazole-coumarin conjugate
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DOI：
10.1016/j.tetlet.2013.12.109
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发表时间：
2014-02-05
影响因子：
1.8
通讯作者：
Chang, Suk-Kyu
中科院分区：
文献类型：
--
作者：
Bae, Jihee;Choi, Jiyoung;Chang, Suk-Kyu
研究了一种基于反应的硫化氢（H2S）双信号传导探针。h2s诱导的7-硝基-2,1,3-苯并恶二唑（NBD）和7-羟基香豆素偶联物醚键的选择性断裂导致了双重信号行为。比色和荧光信号行为分别归因于h2s诱导生成的7-硝基苯-2,1,3-恶二唑-4-硫醇（NBD-SH）和7-羟基香豆素。用比值法分析了其信号行为。在DMSO水溶液中，H2S对其他常见金属离子和阴离子的选择性信号传导是可能的，检测限为1.6 x 10(-6) M。(C) 2014 Elsevier Ltd.版权所有。
A novel reaction-based probe for the dual signaling of hydrogen sulfide (H2S) was investigated. The selective H2S-induced cleavage of the ether linkage of the 7-nitro-2,1,3-benzoxadiazole (NBD) and 7-hydroxycoumarin conjugate resulted in a dual signaling behavior. The colorimetric and fluorogenic signaling behaviors were attributed to the H2S-induced generation of 7-nitrobenzo-2,1,3-oxadiazole-4-thiol (NBD-SH) and 7-hydroxycoumarin, respectively. The signaling behavior was analyzed by ratiometry. The selective signaling of H2S over other common metal ions and anions was possible with a detection limit of 1.6 x 10(-6) M in an aqueous DMSO solution. (C) 2014 Elsevier Ltd. All rights reserved.