Divergent approach for synthesis and terminal modifications of dendritic polyphenylazomethines
Divergent approach for synthesis and terminal modifications of dendritic polyphenylazomethines
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DOI：
10.1021/ol701925a
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发表时间：
2007-12-06
期刊：
影响因子：
5.2
通讯作者：
Yamamoto, Kimihisa
中科院分区：
文献类型：
--
作者：
Takanashi, Kensaku;Yamamoto, Kimihisa
过去，树枝状聚苯偶氮次甲基（DPA）是通过收敛法合成的。然而，收敛方法存在终端组修改困难、步骤数量增加等问题。因此，我们通过发散法合成了末端保护的DPA来构建树枝状结构。收敛法和发散法的结合很容易实现了更高代树枝状聚合物的快速合成。此外，我们利用酯-DPA通过发散法成功合成了水溶性PEG-DPA。
In the past, dendritic polyphenylazomethines (DPA) have been synthesized via the convergent method. However, the convergent method has problems such as difficult terminal-group modifications and an increased number of steps. Therefore, we synthesized the terminal-protected DPA to construct the dendritic structure via the divergent method. The combination of the convergent method and the divergent method easily achieved the rapid synthesis of a higher generation dendrimer. Furthermore, we succeeded in the synthesis of the water-soluble PEG-DPA via the divergent method using the ester-DPA.