A Distinctive Genetic Footprint of Ancient Hybridization
A Distinctive Genetic Footprint of Ancient Hybridization
复制标题
古代杂交的独特遗传足迹
DOI：
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
M. Venkatraman
中科院分区：
文献类型：
--
作者：
J. McCormack;M. Venkatraman
摘要。
古代杂交很难检测，并且通常是从表型和遗传数据集之间的冲突模式中推测出来的，这些模式很难用替代假设来解释。在这里，一个偶然的宏突变的微卫星位点允许一个异常独特的足迹古代基因渗入推断之间的两个高度不同的鸟类物种，开始在晚中新世形成。在墨西哥松鸦（Aphelocoma wollweberi）的一个基因座上有一个独特的高重复数（大）等位基因的渐变群，它主要具有低重复数（小）等位基因，在跨火山松鸦（A. ultramarina），其对于大等位基因是固定的，指示基因流。然而，基因流动并不是最近才发生的，因为墨西哥松鸦和跨火山松鸦之间很少有等位基因状态。古代的基因流也比现在的基因流更合理，因为先前的线粒体DNA结果显示，没有证据表明目前的物种分布范围之间的分散，和墨西哥松鸦与渗入的大等位基因的表型更类似于Transvolcanic松鸦，如预期与最近的杂交。虽然在生命树的分叉往往被认为是掩盖了复杂的历史的渗入，我们的研究结果提供了一些最清楚的证据表明，物种形成可以生存一个或多个回合的基因流没有检测到的痕迹，在表型和mtDNA的组成物种。
ABSTRACT.
Ancient hybridization is difficult to detect and is often surmised from conflicting patterns between phenotypic and genetic data sets that are difficult to explain with alternative hypotheses. Here, a fortuitous macromutation in a microsatellite locus allows an unusually distinctive footprint of ancient introgression to be inferred between two highly divergent bird species that began to speciate in the Late Miocene. A cline of distinctive high-repeat-number (large) alleles at a locus in the Mexican Jay (Aphelocoma wollweberi), which predominantly has low-repeat-number (small) alleles, reaches its highest frequency near the range border with Transvolcanic Jays (A. ultramarina), which are fixed for large alleles, indicating gene flow. The gene flow is not recent, however, because very few of the allelic states are shared between Mexican Jays and Transvolcanic Jays. Ancient gene flow is also more plausible than current gene flow because prior mitochondrial DNA results show no evidence of current dispersal between the ranges of the species, and Mexican Jays with introgressed large alleles are not phenotypically more similar to Transvolcanic Jays, as would be expected with recent hybridization. Although bifurcations in the tree of life are often assumed to belie complex histories of introgression, our results provide some of the clearest evidence that speciation can survive one or multiple bouts of gene flow with no detectable trace in the phenotypes and mtDNA of the constituent species.
影响因子：
10.7
作者：
Durand, Eric Y.;Patterson, Nick;Slatkin, Montgomery
通讯作者：
Slatkin, Montgomery