Longitudinal changes in hearing sensitivity among men: The Veterans Affairs Normative Aging Study

Longitudinal changes in hearing sensitivity among men: The Veterans Affairs Normative Aging Study
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DOI:
10.1121/1.3466878
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发表时间:
2010-10-01
影响因子:
2.4
通讯作者:
Spiro, Avron, III
Spiro, Avron, III
中科院分区:
物理与天体物理3区
文献类型:
--
作者:
Echt, Katharina V.;Smith, Sherri L.;Spiro, Avron, III

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在35年(1962-1996)的时间里,退伍军人事务部规范性老龄化研究(NAS)的参与者完成了多达8次听力评估,这是一项男性健康老龄化研究。本报告描述了年龄相关的听力轨迹筛选男性(n=953)年龄在23至81岁的登记,估计每十年的听力灵敏度的变化率,并比较了纵向和横截面的听力灵敏度的变化估计。这些人平均被跟踪了14年。听力轨迹,基于混合效应模型分析方法的数据,提供了收敛的证据表明,听力损失在老龄化是普遍和渐进的,即使在男性最初选择的身体健康。一般来说,这些人在40岁出头开始在较高频率下的听力灵敏度出现早期损失(>25 dB HL),但在较低频率下的听力阈值保持在25 dB HL以上,直到老年。频率和年龄之间的平均每年变化率为0.69 dB。预测的听力灵敏度变化的横截面估计可靠地近似纵向轨迹,在第8个十年有轻微的错误估计。[DOI 10.1121/1.3466878]
Over 35 years (1962-1996), participants of the Veterans Affairs Normative Aging Study (NAS), a study of healthy aging in men, completed up to eight audiometric assessments. This report describes the age-related hearing trajectories of screened men (n=953) aged 23 to 81 years at enrollment, estimates the typical rate of change per decade in hearing sensitivity, and compares longitudinal and cross-sectional estimates of change in hearing sensitivity. The men were followed 14 years on average. The hearing trajectories, based on a mixed-effects model analytical approach to the data, provide converging evidence that hearing loss in aging is pervasive and progressive even among men initially selected for good physical health. Typically the men accrued early losses (>25 dB HL) in hearing sensitivity at the higher frequencies beginning in the early 40s, but maintained hearing thresholds better than 25 dB HL for lower frequencies into old age. The average rate of change per year across frequencies and age was 0.69 dB. Predicted cross-sectional estimates of change in hearing sensitivity reliably approximated longitudinal trajectories, with slight misestimations in the 8(th) decade. [DOI: 10.1121/1.3466878]