Spreading of sexually transmitted diseases in heterosexual populations
Spreading of sexually transmitted diseases in heterosexual populations
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DOI：
10.1073/pnas.0707332105
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发表时间：
2008-02-05
影响因子：
11.1
通讯作者：
Profumo, Elio
中科院分区：
文献类型：
--
作者：
Gomez-Gardenes, Jesus;Latora, Vito;Profumo, Elio
性传播疾病的传播（例如，衣原体、梅毒、淋病、艾滋病毒等）是科学家和卫生机构的主要关注点。在这种情况下，性接触网络的数据收集和疾病传播的建模都是对寻求有效免疫政策的重大贡献。在这里，传播性传播疾病的二分无标度图，代表异性接触网络，被认为是。我们解析地推导出在有限种群中的流行病阈值的表达式及其与系统规模的依赖关系。我们表明，流行病爆发的双向人口，与分布在全国性调查的经验观察的性伴侣的数量，发生更大的传播速度比的情况下，其中的网络的双向性质不考虑在内。数值模拟验证了理论结果的正确性。我们的研究结果表明，在设计有效的性传播疾病免疫策略时，必须考虑到对两类个体（男性和女性）之间交叉感染的限制。
The spread of sexually transmitted diseases (e.g., chlamydia, syphilis, gonorrhea, HIV, etc.) across populations is a major concern for scientists and health agencies. In this context, both the data collection on sexual contact networks and the modeling of disease spreading are intensive contributions to the search for effective immunization policies. Here, the spreading of sexually transmitted diseases on bipartite scale-free graphs, representing heterosexual contact networks, is considered. We analytically derive the expression for the epidemic threshold and its dependence with the system size in finite populations. We show that the epidemic outbreak in bipartite populations, with number of sexual partners distributed as in empirical observations from national sex surveys, takes place for larger spreading rates than for the case in which the bipartite nature of the network is not taken into account. Numerical simulations confirm the validity of the theoretical results. Our findings indicate that the restriction to crossed infections between the two classes of individuals (males and females) has to be taken into account in the design of efficient immunization strategies for sexually transmitted diseases.