Detection of preinvasive cancer cells
Detection of preinvasive cancer cells
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DOI：
10.1038/35017638
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发表时间：
2000-07-06
期刊：
影响因子：
64.8
通讯作者：
Feld, MS
中科院分区：
文献类型：
--
作者：
Backman, V;Wallace, MB;Feld, MS
超过85%的癌症起源于上皮细胞，这些上皮细胞排列在整个身体器官的内表面。虽然这些是很容易治疗的，只要他们在一个前侵入阶段诊断，早期病变往往几乎不可能检测到。在这里，我们提出了一种新的光学探针技术的基础上，光散射光谱，能够检测癌前病变和早期癌细胞丰富的上皮细胞的变化。
More than 85% of all cancers originate in the epithelium that lines the internal surfaces of organs throughout the body. Although these are readily treatable provided they are diagnosed in one of the preinvasive stages, early lesions are often almost impossible to detect. Here we present a new optical-probe technique based on light-scattering spectroscopy that is able to detect precancerous and early cancerous changes in cell-rich epithelia.