Recolonisation pattern of mutans streptococci after suppression by three different modes of chlorhexidine gel application.
Recolonisation pattern of mutans streptococci after suppression by three different modes of chlorhexidine gel application.
复制标题
通过三种不同模式的氯己定凝胶应用抑制后变形链球菌的再定殖模式。
DOI：
10.1046/j.0909-8836.1999.eos1070303.x
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发表时间：
1999
影响因子：
1.9
通讯作者：
D. Birkhed
中科院分区：
文献类型：
--
作者：
C. Emilson;H. Gisselsson;D. Birkhed
临床研究表明，当洗必泰凝胶用于牙托或牙线时，对减少邻面龋的结果相互矛盾。为了研究这些治疗模式是否会不同程度地影响变形链球菌（MS）的定植，我们在单次洗必泰凝胶应用前后对唾液和各种牙齿表面的MS进行了定量。二十一名学童（15-16岁），与大量的唾液MS，被随机分为三组。受试者使用1%氯己定凝胶进行治疗：1）牙间牙线; 2）单独设计的口托;或3）抛光和牙线的组合。唾液和牙菌斑从12个网站超过8周的分析表明，更大的减少唾液MS计数和定植的网站总数在托盘组比牙线组。抛光-牙线组对MS的影响接近托盘组。在牙间区域，托盘治疗后没有检测到MS（评分为0）的部位比使用牙线后更多，而使用牙线组中重度定植部位（评分为3+/-4）的减少率更高。凝胶治疗后，牙线组中3+/-4分的部位的重现比其他两组更快。总之，结果表明，所有三种方法都能暂时减少MS定植，并且在口托盘中或作为抛光和牙线的组合应用氯己定凝胶比单独使用牙线更有效地减少MS群体。
Clinical studies have shown conflicting results for the reduction of approximal caries when chlorhexidine gel has been applied either in trays or by flossing. To investigate whether these modes of treatment affect the colonization of mutans streptococci (MS) differently, we quantified MS in saliva and on various tooth surfaces before and after a single chlorhexidine gel application. Twenty-one schoolchildren (15-16 yr old), with high numbers of salivary MS, were randomised into three groups. The subjects were treated with a 1% chlorhexidine gel applied either by: 1) interdental flossing; 2) individually designed mouth trays; or 3) a combination of polishing and flossing. Analysis of saliva and of dental plaque from 12 sites over an 8-wk period showed a greater reduction of both salivary MS counts and total number of colonised sites in the tray group than in the flossing group. The effect on MS in the polishing-flossing group approached that obtained in the tray group. In the interdental areas, more sites had no detectable MS (score 0) after tray treatment than after flossing, whereas the reduction of heavily colonised sites (scores 3+/-4) was higher in the flossing group. The reappearance of sites with score 3+/-4 after the gel treatment was more rapid in the flossing group than in the other two groups. In conclusion, the results showed a transient reduction of MS colonisation by all three methods, and that the application of the chlorhexidine gel both in mouth trays or as a combination of polishing and flossing was more effective in reducing the MS population than flossing alone.