Life expectancy of type 1 diabetic patients during 1997-2010: a national Australian registry-based cohort study
Life expectancy of type 1 diabetic patients during 1997-2010: a national Australian registry-based cohort study
复制标题
DOI：
10.1007/s00125-015-3857-4
复制
发表时间：
2016-06-01
期刊：
影响因子：
8.2
通讯作者：
Magliano, Dianna J.
中科院分区：
文献类型：
--
作者：
Huo, Lili;Harding, Jessica L.;Magliano, Dianna J.
目的/假设在当代人群中，关于1型糖尿病对预期寿命影响的信息有限。我们检查了1型糖尿病患者的预期寿命，并与一般人群相比，探讨了不同年龄和不同死因的死亡率对生命损失年数（YLL）的贡献。方法通过将NDSS与国家死亡指数联系起来，得出1997年至2010年间列入国家糖尿病服务计划（NDSS）的澳大利亚1型糖尿病患者的死亡率（n=85,547）。蒋方法用于估计预期寿命，Arriaga方法用于估计年龄特异性和病因特异性死亡率对YLL的贡献。结果在902136人-年的随访中，共有5981人死亡。1型糖尿病患者出生时的预期寿命估计为68.6岁（95% CI 68.1, 69.1），比一般人群少12.2岁（95% CI 11.8, 12.7）。与1997-2003年相比，2004-2010年1型糖尿病患者（男性，1.9岁[95% CI 0.4, 3.3]；女性，1.5岁[95% CI 0.0, 3.2]）和一般人群（男性，2.2岁；女性，1.4岁）出生时预期寿命的改善相似。死亡年龄= 40岁（男性43-75%；女性34-75%）。结论/解释1997年至2010年的数据显示，澳大利亚1型糖尿病患者出生时的预期寿命与一般人群相比估计减少了12.2年。
Aims/hypothesis There is limited information about the impact of type 1 diabetes on life expectancy in a contemporary population. We examined the life expectancy of type 1 diabetic patients and explored the contribution of mortality at different ages and of different causes of death to years of life lost (YLL) compared with the general population.Methods We derived mortality rates of Australians with type 1 diabetes listed on the National Diabetes Services Scheme (NDSS) between 1997 and 2010 (n=85,547) by linking the NDSS to the National Death Index. The Chiang method was used to estimate life expectancy and Arriaga's method was used to estimate the contributions of age-specific and cause-specific mortality to the YLL.Results A total of 5,981 deaths were identified during the 902,136 person-years of follow up. Type 1 diabetic patients had an estimated life expectancy at birth of 68.6 years (95% CI 68.1, 69.1), which was 12.2 years (95% CI 11.8, 12.7) less than that in the general population. The improvement in life expectancy at birth in 2004-2010 compared with 1997-2003 was similar for both type 1 diabetic patients (men, 1.9 years [95% CI 0.4, 3.3]; women, 1.5 years [95% CI 0.0, 3.2]) and the general population (men, 2.2 years; women, 1.4 years). Deaths at age = 40 years (men, 43-75%; women, 34-75%).Conclusions/interpretation Data from 1997 to 2010 showed that Australian type 1 diabetic patients had an estimated loss in life expectancy at birth of 12.2 years compared with the general population.