Sclerosing odontogenic carcinoma: current diagnostic and management considerations concerning a most unusual neoplasm
Sclerosing odontogenic carcinoma: current diagnostic and management considerations concerning a most unusual neoplasm
复制标题
DOI：
10.1016/j.ijom.2017.05.024
复制
发表时间：
2017-12-01
影响因子：
2.4
通讯作者：
Jung, S.
中科院分区：
文献类型：
--
作者：
Hanisch, M.;Baumhoer, D.;Jung, S.
硬化性牙源性癌（SOC）是颌骨的原发性骨内癌，在最新版的世界卫生组织头颈部肿瘤分类（2017）中首次被列为一个单独的实体。本研究的目的是在作者所在科室治疗的临床病例的背景下分析和解释SOC的现有文献。根据PRISMA指南对PubMed数据库进行了系统检索，迄今为止报告了9例SOC病例。总之，SOC的特征性临床和放射学特征包括无症状肿胀、主要位于下颌骨、肿瘤外观主要为溶解性、存在皮质骨破坏和无转移性扩散。由于这种疾病的罕见性，口腔/颌面外科医生和病理学家之间的密切合作是至关重要的，以避免误诊。完全切除后，预计SOC不会复发。
Sclerosing odontogenic carcinoma (SOC) is a primary intraosseous carcinoma of the jaws that has been listed as a separate entity for the first time in the latest version of the World Health Organization classification of Head and Neck Tumours (2017). The aim of this study was to analyse and interpret the existing literature on SOC in the context of a clinical case treated in the authors' department. A systematic search of the PubMed database was performed in accordance with the PRISMA guidelines, yielding nine cases of SOC reported so far. In summary, characteristic clinical and radiological features of SOC include asymptomatic swelling, location predominantly in the mandible, tumour primarily lytic in appearance, presence of cortical bone destruction, and lack of metastatic spread. Due to the rarity of the disease, close collaboration between oral/maxillofacial surgeons and pathologists is crucial to avoid misdiagnosis. With complete excision, no recurrence of SOC should be expected.