Steady-state MR imaging with MION for quantification of angiogenesis in normal brain and in brain tumors.
Steady-state MR imaging with MION for quantification of angiogenesis in normal brain and in brain tumors.
复制标题
使用 MION 进行稳态 MR 成像，用于量化正常大脑和脑肿瘤中的血管生成。
DOI：
10.1007/978-1-4757-6125-2_31
复制
发表时间：
2003
影响因子：
--
通讯作者：
Makki,Malek
中科院分区：
文献类型：
--
作者：
Dunn,JeffF;Roche,MarcieA;Springett,Roger;Abajian,Michelle;Merlis,Jennifer;Daghlian,CharlesP;Lu,ShiY;O'Hara,JuliaA;Makki,Malek
血管生成在脑对低氧应激的正常反应中以及在许多病理条件如中风和肿瘤生长中起作用。血管生成或新毛细血管的生长将改善脑缺血区域的血流，并且抑制血管生成现在是新抗癌剂的主要目标。
Angiogenesis plays a role in the normal response of brain to low oxygen stress, as well as in many pathological conditions such as stroke and tumor growth. Angiogenesis, or the growth of new capillaries, will improve flow to ischemic areas of the brain, and the inhibition of angiogenesis is now a major target of new anti-cancer agents.