Imaging of the lungs using 3He MRI: Preliminary clinical experience in 18 patients with and without lung disease

Imaging of the lungs using 3He MRI: Preliminary clinical experience in 18 patients with and without lung disease
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DOI:
10.1002/jmri.1880070314
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发表时间:
1997-05-01
期刊:
JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING
影响因子:
--
通讯作者:
Thelen, M
Thelen, M
中科院分区:
其他
文献类型:
--
作者:
Kauczor, HU;Ebert, M;Thelen, M

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本研究的目的是描述健康志愿者正常肺通气的3He MRI表现,并评估不同肺部疾病患者的异常情况,8名健康志愿者和10名不同肺部疾病患者吸入超极化3He气体(300 ml, 3 × 10(5) Pa,光泵极化至35-45%,提供在特殊的玻璃细胞中)。成像采用三维快速低角度拍摄(FLASH)序列(TR = 11.8 msec; TE = 5 msec;发射机振幅5-8 V;
The purpose of this study was to describe the 3He MRI findings of normal pulmonary ventilation in healthy volunteers and to evaluate abnormalities in patients with different lung diseases, Hyperpolarized 3He gas (300 ml, 3 x 10(5) Pa, polarized to 35-45% by optical pumping, provided in special glass cells) was inhaled by 8 healthy volunteers and 10 patients with different lung diseases. Imaging was performed with a three-dimensional fast low-angle shot (FLASH) sequence (TR = 11.8 msec; TE = 5 msec; transmitter amplitude, 5-8 V; corresponding nip angle,