Rectovesical fistula: a possible cause of postnatal lethality in F1 Dh/+ male mice between DDD female and DH (Dh/+) male.
Rectovesical fistula: a possible cause of postnatal lethality in F1 Dh/+ male mice between DDD female and DH (Dh/+) male.
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直肠膀胱瘘：DDD 雌性和 DH (Dh/ ) 雄性之间的 F1 Dh/ 雄性小鼠产后致死的可能原因。
DOI：
10.1538/expanim.45.399
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发表时间：
1996
影响因子：
2.4
通讯作者：
K. Imamura
中科院分区：
文献类型：
--
作者：
J. Suto;K. Imamura
为了揭示DDD x Dh （Dh/+）交配F1 Dh/+雄性小鼠出生后死亡的主要原因，本研究进行了。Dh/+雄性在出生后几天内出现发育迟缓。在22只Dh/+雄性小鼠中，有9只发现了直肠和膀胱之间不寻常的连接处（直肠膀胱瘘），膀胱中含有来自肠道的不寻常物质。当发现瘘管时，尿液总是凝胶状的，8例肛门闭锁，提示患者排尿和排泄有困难。从这些观察我们得出结论，直肠膀胱瘘是F1 Dh/+男性出生后死亡的主要原因。
To reveal a major cause of postnatal lethality in F1 Dh/+ male mice from DDD x DH (Dh/+) mating, the current study was performed. Dh/+ males with retarded growth appeared within a few days after birth. The unusual junction between the rectum and the urinary bladder (rectovesical fistula) was found in nine of 22 Dh/+ male mice, and the bladder contained unusual substances derived from the intestines. When the fistula was recognized, the urine was always gelatinous, and the anus was imperforate in eight cases, suggesting that an affected individual would have trouble in urination and evacuation. From these observations we conclude that the rectovesical fistula is a major cause of postnatal death in the F1 Dh/+ male.