Correlation of Body Composition and Nutritional Status with Functional Recovery in Stroke Rehabilitation Patients
Correlation of Body Composition and Nutritional Status with Functional Recovery in Stroke Rehabilitation Patients
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DOI：
10.3390/nu12071923
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发表时间：
2020-07-01
期刊：
影响因子：
5.9
通讯作者：
Mizushima, Takashi
中科院分区：
文献类型：
--
作者：
Irisawa, Hiroshi;Mizushima, Takashi
以往的研究表明，脑卒中后的营养状况与长期预后独立相关，肌肉减少症延迟脑卒中后康复并影响预后。然而，许多中风患者在急性期营养状况恶化，肌肉质量下降。这项前瞻性研究包括179名中风康复中心的患者。我们进行了生物电阻抗分析，并确定了老年营养风险指数（GNRI），以评估肌肉质量和入院时的营养状况。此外，我们使用功能独立性测量（functional independence Measure，简称FIA）分析了患者入院时和4周后的日常生活活动。此外，我们还评估了运动障碍项目的变化，并检查了与数据的关系。多元回归分析显示，高肌肉率（骨骼肌质量/体重）（比值比OR = 2.43），高相位角（OR = 3.32）和高GNRI（OR = 2.57）与男性和女性患者4周时的运动障碍项目显著相关。在中风急性期通过营养管理和早期康复来维持肌肉质量对中风患者的功能恢复至关重要。
Previous studies have suggested that the nutritional status after stroke is independently associated with long-term outcomes and that sarcopenia delays poststroke rehabilitation and worsens the prognosis. However, many stroke patients have a deteriorated nutritional status and a decreased muscle mass in the acute phase. This prospective study included 179 patients who were admitted to the stroke rehabilitation unit. We performed bioelectrical impedance analysis and determined the Geriatric Nutritional Risk Index (GNRI) to assess muscle mass and the nutritional status on admission. Furthermore, we analyzed the activities of daily living using the Functional Independence Measure (FIM) at the time of admission and four weeks later. Furthermore, we evaluated the change in motor FIM items and examined the relationship with the data. Multiple regression analysis revealed that a high muscle rate (skeletal muscle mass/body weight) (odds ratio OR = 2.43), high phase angle (OR = 3.32), and high GNRI (OR = 2.57) were significantly associated with motor FIM items at four weeks in male and female patients. Muscle mass maintenance through nutritional management and early rehabilitation in the acute period of stroke is essential for functional recovery in stroke patients.