THE PREVALENCE OF GILBERTS-SYNDROME IN GERMANY
THE PREVALENCE OF GILBERTS-SYNDROME IN GERMANY
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DOI：
10.1055/s-2008-1068222
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发表时间：
1987-07-31
影响因子：
0.6
通讯作者：
KOMMERELL, B
中科院分区：
文献类型：
--
作者：
SIEG, A;ARAB, L;KOMMERELL, B
对居住在联邦共和国德国海德堡地区的1530人（785名男性和745名女性，年龄20-40岁）的随机分组进行了Gilbert综合征患病率研究。发现12.4%的男性和4.8%的女性患有这种疾病，即整个群体的患病率为8.6%。在女性中，血清胆红素水平（平均12.0 ±. 5.1μ mol/l）显著低于男性（平均值为13.7 ± 1.5 μ mol/l）。6.8μ mol/l; P < 0.001）。分析血清胆红素的频率分布显示，患有该综合征的患者不构成其自身的人群，而是形成标准胆红素分布曲线的上端。
The prevalence of Gilbert''s syndrome was studied in a randomized group of 1530 persons (785 men and 745 women, aged 20-40 years) living in the Heidelberg region of the Federal Republic of Germany. It was found to be present in 12.4% of men and 4.8% of women, i.e. a total of 8.6% for the entire group. In women the serum bilirubin level (mean 12.0 .+-. 5.1 .mu.mol/l) was significantly lower than in men (mean of 13.7 .+-. 6.8 .mu.mol/l; P < 0.001). Analysing the frequency distribution of serum bilirubin revealed that patients with this syndrome do not constitute a population of its own, but rather form the upper end of the normative bilirubin distribution curve.