Detection of point mutations in rpoB gene of rifampin-resistant Rickettsia typhi.
Detection of point mutations in rpoB gene of rifampin-resistant Rickettsia typhi.
复制标题
耐利福平伤寒立克次体rpoB基因点突变的检测
DOI:
10.1128/aac.42.7.1845
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发表时间:
1998
影响因子:
4.9
通讯作者:
Azad,AF
中科院分区:
文献类型:
--
作者:
Troyer,JM;Radulovic,S;Andersson,SG;Azad,AF
TherpoBgene of rifampin-resistantRickettsia typhi(Rif mutant) and wild-typeR. typhiwere sequenced and compared. The Rif mutantrpoBhad three nucleotide substitutions, which resulted in amino acid changes at residues 151, 201, and 271 and may be the basis for the rifampin resistance.