Worldwide incidence of multidrug-resistant tuberculosis
Worldwide incidence of multidrug-resistant tuberculosis
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DOI：
10.1086/339818
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发表时间：
2002-04-15
影响因子：
6.4
通讯作者：
Williams, BG
中科院分区：
文献类型：
--
作者：
Dye, C;Espinal, MA;Williams, BG
结核病控制规划需要对耐药病例的数量和分布进行评估。这项研究利用64个国家的耐药调查结果以及来自其他72个国家的耐药率预测数据，来估计2000年发生的耐多药结核病新病例数。通过这些方法，2000年全世界估计发生了27.3万例（95%置信限，18.5万例和41.4万例）耐多药结核病新发病例，占所有结核病新发病例的3.2%。该分析提供了第一套按国家和全球分列的耐多药结核病负担综合估计数。
Planning for tuberculosis (TB) control requires an assessment of the number and distribution of drug-resistant cases. This study used results of resistance surveys from 64 countries, together with data predictive of resistance rates from 72 others, to estimate the number of new multidrug-resistant (MDR) TB cases that occurred in 2000. By these methods, an estimated 273,000 (95% confidence limits, 185, 000 and 414, 000) new cases of MDR TB occurred worldwide in 2000, 3.2% of all new TB cases. The analysis provides the first comprehensive set of estimates of the MDR TB burden by country and globally.