Miniaturized Battery-Free Wireless Systems for Wearable Pulse Oximetry
Miniaturized Battery-Free Wireless Systems for Wearable Pulse Oximetry
复制标题
用于可穿戴脉搏血氧仪的小型化无电池无线系统
DOI：
10.1002/adfm.201604373
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发表时间：
2017-01-01
影响因子：
19
通讯作者：
Rogers, John A.
中科院分区：
文献类型：
--
作者：
Kim, Jeonghyun;Gutruf, Philipp;Rogers, John A.
无线采集和定量分析生理状态临床相关信息的非常规技术的发展日益引起人们的兴趣。柔软的生物相容性系统被广泛认为是重要的，因为它们便于安装在身体的外部（如皮肤）和内部（如心脏和大脑）表面。超小型化、轻量化和无电池设备有可能成为生物整合领域的补充选择，因为在指甲和牙齿等坚硬表面上可以实现长期接口（即数月），而刺激或不适的风险可以忽略不计。在这里，作者报告了柔性平台的材料和设备概念，这些平台结合了先进的光电功能，用于无线捕获和传输光电容积图，包括血氧、心率和心率变异性的定量信息。具体来说，反射脉搏血氧仪与近场通信能力相结合，可以在薄的、小型化的柔性设备中操作。对与人体界面相关的材料方面的研究，以及对射频特性、光电数据采集方法和分析方法的研究，涵盖了所有相关的工程考虑因素。在身体不同部位的操作演示和与临床金标准的定量比较分别建立了这些系统的多功能性和测量准确性。
Development of unconventional technologies for wireless collection and analysis of quantitative, clinically relevant information on physiological status is of growing interest. Soft, biocompatible systems are widely regarded as important because they facilitate mounting on external (e.g., skin) and internal (e.g., heart and brain) surfaces of the body. Ultraminiaturized, lightweight, and battery-free devices have the potential to establish complementary options in biointegration, where chronic interfaces (i.e., months) are possible on hard surfaces such as the fingernails and the teeth, with negligible risk for irritation or discomfort. Here, the authors report materials and device concepts for flexible platforms that incorporate advanced optoelectronic functionality for applications in wireless capture and transmission of photoplethysmograms, including quantitative information on blood oxygenation, heart rate, and heart rate variability. Specifically, reflectance pulse oximetry in conjunction with near-field communication capabilities enables operation in thin, miniaturized flexible devices. Studies of the material aspects associated with the body interface, together with investigations of the radio frequency characteristics, the optoelectronic data acquisition approaches, and the analysis methods capture all of the relevant engineering considerations. Demonstrations of operation on various locations of the body and quantitative comparisons to clinical gold standards establish the versatility and the measurement accuracy of these systems, respectively.