Catecholaminotropic effects of catecholamines in a teleost fish, Anguilla rostrata.
Catecholaminotropic effects of catecholamines in a teleost fish, Anguilla rostrata.
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儿茶酚胺对硬骨鱼（Anguilla rostrata）的儿茶酚胺效应。
DOI：
10.1007/bf00687469
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发表时间：
1985
期刊：
影响因子：
--
通讯作者：
Nibbio,B
中科院分区：
文献类型：
--
作者：
Epple,A;Nibbio,B
注射生理和超生理剂量的肾上腺素（E）到cardiacannulated鳗鱼引起血浆多巴胺（DA）和去甲肾上腺素（NE）在3分钟内剂量相关的增加。同样，外源性DA和NE增加各自的其他两个儿茶酚胺（CA）的血浆滴度。NE和E的基线滴度密切相关。NE和E的基线滴度与DA的基线滴度之间缺乏相关性似乎是由于DA从循环中的消失速度更快。E具有强烈的高血糖作用，NE较弱的血糖作用可能是通过E的释放介导的。E的作用似乎取决于喷射样增加，而不是其滴度本身。鳗鱼科普血浆CA快速过度增加的能力提出了潜在机制的问题。
Injections of physiological and supraphysiological doses of epinephrine (E) into cardiaccannulated eels cause a dose-related increase of plasma dopamine (DA) and norepineprine (NE) within 3 min. Likewise, both exogenous DA and NE increase the plasma titers of the respective other two catecholamines (CAs). The baseline titers of NE and E are closely correlated. Lack of a correlation of the baseline titers of NE and E with that of DA appears to be due to a faster disappearance rate of DA from the circulation. E is strongly hyperglycemic, and the weaker glycemic action of NE may be mediated via E release. The effects of E seem to depend on a spurt-like increase rather than its titer per se. The ability of the eel to cope with very fast, excessive increases of plasma CAs raises the question of the underlying mechanisms.